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Accumulation of aggregated α-synuclein into Lewy bodies is thought to contribute to the onset and progression of dopaminergic neuron degeneration in Parkinson’s disease (PD) and related disorders. Although protein aggregation is associated with perturbation of proteostasis, how α-synuclein aggregat...
ORGANISM(S): Mus musculus (Mouse) 
2018-05-18 | PXD009717 | Pride
Trypanosoma brucei Replication Protein A (RPA) complex was purified using Ni-NTA purification where only the RPA1 subunit was tagged with 6x histidine. The purified TbRPA complex was run on SDS-PAGE and all three sub-units were gel sliced, processed and subjected to LC-MS/MS.
ORGANISM(S): Trypanosoma brucei 
2023-06-08 | PXD042808 | Pride
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