Proteotoxicity - OmicsDI

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A Short Peptide Protects from Age-Onset Proteotoxicity

PRJNA962043 | ENA

Cathepsin B Promotes Aβ Proteotoxicity by Modulating Aging Regulating Mechanisms

PRJNA974377 | ENA

Cathepsin B Promotes Aβ Proteotoxicity by Modulating Aging Regulating Mechanisms

While the activities of certain proteases promote proteostasis and prevent neurodegeneration-associated phenotypes, the protease cathepsin B (CTSB) enhances proteotoxicity in Alzheimer’s disease (AD) model mice, and its levels are elevated in brains of AD patients. How CTSB exacerbates the toxicity ...

ORGANISM(S): Caenorhabditis elegans

2024-09-03 | PXD045531 | Pride