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TranscriptomicsA TARBP2-dependent miRNA expression profile determines cancer stem cell properties and provides new candidate therapeutic reagents in Ewing's sarcoma
This SuperSeries is composed of the following subset Series: GSE30513: MicroRNA expression profiling of Ewing sarcoma cancer stem cells GSE31144: MicroRNA expression profiling of Ewing sarcoma cell lines upon TARBP2 depletion GSE31145: MicroRNA expression profiling of Ewing sarcoma spheres vs. adher...
ORGANISM(S): Homo sapiens 
2012-06-19 | E-GEOD-31146 | biostudies-arrayexpress
UnknownThe Length of the Expressed 3' UTR Is an Intermediate Molecular Phenotype Linking Genetic Variants to Complex Diseases.
Not available
S-EPMC6707137 | biostudies-literature
TranscriptomicsMicroRNA expression profiling of Ewing sarcoma cell lines upon TARBP2 depletion
We have recently demonstrated that human paediatric mesenchymal stem cells can be reprogrammed toward a Ewing’s sarcoma family tumor (ESFT) cancer stem cell (CSC) phenotype by mechanisms that implicate microRNAs (miRNAs). Here, we show that the miRNA profile of ESFT CSC is shared by embryonic stem c...
ORGANISM(S): Homo sapiens 
2012-06-19 | E-GEOD-31144 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression profiling of Ewing sarcoma spheres vs. adherent cells
We have recently demonstrated that human paediatric mesenchymal stem cells can be reprogrammed toward a Ewing’s sarcoma family tumor (ESFT) cancer stem cell (CSC) phenotype by mechanisms that implicate microRNAs (miRNAs). Here, we show that the miRNA profile of ESFT CSC is shared by embryonic stem c...
ORGANISM(S): Homo sapiens 
2012-06-19 | E-GEOD-31145 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression profiling of Ewing sarcoma cancer stem cells
We have recently demonstrated that human paediatric mesenchymal stem cells can be reprogrammed toward a Ewing’s sarcoma family tumor (ESFT) cancer stem cell (CSC) phenotype by mechanisms that implicate microRNAs (miRNAs). Here, we show that the miRNA profile of ESFT CSC is shared by embryonic stem c...
ORGANISM(S): Homo sapiens 
2012-06-19 | E-GEOD-30513 | biostudies-arrayexpress
UnknownSP1 and STAT3 Functionally Synergize to Induce the RhoU Small GTPase and a Subclass of Non-canonical WNT Responsive Genes Correlating with Poor Prognosis in Breast Cancer.
Not available
S-EPMC6356433 | biostudies-literature
TranscriptomicsIdentification of p130Cas/ErbB2-dependent invasive signatures in transformed mammary epithelial cells
Understanding transcriptional changes during cancer progression is of crucial importance to develop new and more efficacious diagnostic and therapeutic approaches. It is well known that ErbB2 is overexpressed in about 25% of human invasive breast cancers. We have previously demonstrated that p130Cas...
ORGANISM(S): Homo sapiens 
2013-07-22 | E-GEOD-42949 | biostudies-arrayexpress
TranscriptomicsmiR-148b modulates the expression of multiple genes
To identify which miR-148b targets were involved in tumorigenesis, a microarray analysis was performed for miR-148b over-expressing cells versus controls and 129 (49 up and 80 down) modulated genes were revealed. The effects of miR-148b on cancer progression depend on the direct and indirect regulat...
ORGANISM(S): Homo sapiens 
2012-12-16 | E-GEOD-26662 | biostudies-arrayexpress
GenomicsPhysical and functional CSL-p53 interactions underlie control of cancer stromal cell evolution [ChIP-seq]
Senescence of stromal fibroblasts has been linked to establishment of cancer associated fibroblasts (CAF) and aging-associated increase of tumors. However, in clinically occurring carcinomas, density and proliferation of CAFs are frequently increased rather than decreased. We previously showed that ...
ORGANISM(S): Homo sapiens 
2015-08-24 | E-GEOD-59942 | biostudies-arrayexpress
UnknownStroma-derived miR-214 coordinates tumor dissemination.
Not available
S-EPMC9837925 | biostudies-literature
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