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ProteomicsProteomic analysis of Psmd9 overexpression in the liver
We have shown that increasing psmd9 expression effects lipid metabolism in vivo and we were interested in investigating the pathways by which psmd9 elicited these changes. To investigate these mechanisms, we performed proteomic analyses on the livers from C57 mice that had been treated with control ...
ORGANISM(S): Mus musculus (Mouse) 
2019-11-01 | PXD007285 | Pride
Liver Adenovirus Psmd9 overexpression 
UnknownComprehensive analysis of PSMD family members and validation of PSMD9 as a potential therapeutic target in human glioblastoma.
Not available
S-EPMC10848081 | biostudies-literature
TranscriptomicsEpCAM overexpression prolongs proliferative capacity of primary human breast epithelial cells and supports hyperplastic growth
Background: The Epithelial Cell Adhesion Molecule (EpCAM) has been shown to be strongly expressed in human breast cancer and cancer stem cells and its overexpression has been supposed to support tumor progression and metastasis. However, effects of EpCAM overexpression on normal breast epithelial ce...
ORGANISM(S): Homo sapiens 
2013-06-20 | E-GEOD-37172 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling by array of human primary keratinocytes to find new genes regulated by p21
Our goal is to find new genes regulated by p21 in human primary cells . To get it we carried out a gene expression profiling in two different models, human myeloid leukemia K562 cells and human keratinocytes both of them with conditional expression of p21. In order to identify genes specifically mo...
ORGANISM(S): Homo sapiens 
2012-04-30 | E-MEXP-3430 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human embryonic kidney cell line HEK293T to investigate the effects of overexpression of FoxO4 or mutated FoxO4 in presence or absence of p300
Effects of overexpression of FoxO4 or mutated FoxO4 in presence or absence of p300 overexpression
ORGANISM(S): Homo sapiens 
2009-07-30 | E-MTAB-4 | biostudies-arrayexpress
Transcriptomicsp21 as a transcriptional co-represor of S-phase and mitotic control genes-kp21
Our goal is to find new genes regulated by p21 in human primary cells . To get it we carried out a gene expression profiling in two different models, human myeloid leukemia K562 cells and human keratinocytes both of them with conditional expression of p21. In order to find genes regulated by p21 in...
ORGANISM(S): Homo sapiens 
2012-05-30 | E-MEXP-3431 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human leukemia cell lines reveals Myc inhibits p27-induced erythroid differentiation
Comparision of genes regulated by Myc in leukemic cells with overexpression of p27
ORGANISM(S): Homo sapiens 
2009-01-10 | E-MEXP-1772 | biostudies-arrayexpress
TranscriptomicsThe anti-proliferative effects of progestins in T47D breast cancer cells are tempered by progestin-induction of the ETS transcription factor Elf5.
Prolactin and progesterone act together to regulate mammary alveolar development, and both hormones have been implicated in breast cancer initiation and progression. Here we show that Elf5, a prolactin-induced ETS transcription factor that specifies the mammary secretory cell lineage, is also induce...
ORGANISM(S): Homo sapiens 
2010-07-08 | E-GEOD-22363 | biostudies-arrayexpress
TranscriptomicsTranscriptional changes in IL-2, IL-12 and IL-18 stimulated human natural killer cells
We used Affymetrix expression arrays to determine changes in gene expression associated with activation of human NK cells mediated through treatment with cytokines IL-2, IL-12 and IL-18 over a 24 hour period. Human natural killer cells were isolated via negative selection from PBMCs of healthy donor...
ORGANISM(S): Homo sapiens 
2010-08-05 | E-GEOD-22919 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling by array of mouse livers expressing transgenic microRNA-221 to study liver oncogenicity
Characterization of a transgenic mouse expressing miR-221 in the liver
ORGANISM(S): Mus musculus 
2012-02-01 | E-TABM-1203 | biostudies-arrayexpress
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