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ProteomicsFLEXIQuant-LF: Robust Regression to quantify protein modification extent in label-free proteomics data
Improvements in LC-MS/MS methods and technology have enabled the identification of thousands of modified peptides in a single experiment. However, protein regulation by post-translational modifications (PTMs) is not binary, making methods to quantify the modification extent crucial to fully understa...
ORGANISM(S): Homo sapiens (Human) 
2020-12-04 | PXD018411 | Pride
Dia Mass spectrometry Modification stochiometry Peptide modification Software Ptm quantification Ptm identification Open source Label-free quantification Dda 
ProteomicsmultiFLEX-LF: A Computational Approach to Quantify the Modification Stoichiometries in Label-free Proteomics Datasets
In high-throughput LC-MS/MS-based proteomics, information about the presence and stoichiometry of post-translational modifications is normally not readily available. To overcome this problem we developed multiFLEX-LF, a computational tool that builds upon FLEXIQuant and FLEXIQuant-LF, which detect m...
ORGANISM(S): Homo sapiens (Human) 
2022-02-11 | PXD027970 | Pride
Dia Post-translational modifications Ptm stochiometry Cell cycle Lc-msms Quantification 
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