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ProteomicsCharacteristics of Mycobacterium tuberculosis PtpA interaction and activity on the alpha subunit of human mitochondrial trifunctional protein, a key enzyme of lipid metabolism
Characteristics of Mycobacterium tuberculosis PtpA interaction and activity on the alpha subunit of human mitochondrial trifunctional protein, a key enzyme of lipid metabolism
ORGANISM(S): Escherichia coli 
2023-06-29 | PXD038119 | Pride
Ptpa Echa Phosphorylation 
GenomicsMycobacterium tuberculosis PtpA ChIP-chip on U937 cells using Monoclonal ANTI-FLAG(R) M2 antibody
We found that Mtb PtpA also enters into the nucleus of host cells, we thus sought to investigate how nuclear PtpA regulates host gene expression.
ORGANISM(S): Homo sapiens 
2017-06-07 | GSE99712 | GEO
GenomicsAltered PPP2R4 (PTPA) expression affects growth and carboplatin response of human malignant pleural mesothelioma cells
Altered PPP2R4 (PTPA) expression affects growth and carboplatin response of human malignant pleural mesothelioma cells
PRJNA1372055 | ENA
TranscriptomicsAltered PPP2R4 (PTPA) expression affects growth and carboplatin response of human malignant pleural mesothelioma cells
Malignant pleural mesothelioma (MPM) is a rare cancer of the pleural surfaces, frequently related to asbestos exposure. It is characterized by a grim prognosis and low survival, as few therapeutic options are currently available. Molecular genomics studies have revealed high molecular heterogeneity,...
ORGANISM(S): Homo sapiens 
2026-08-19 | GSE312009 | GEO
UnknownThe mycobacterial phosphatase PtpA regulates the expression of host genes and promotes cell proliferation.
Not available
S-EPMC5557760 | biostudies-literature
UnknownStructural basis of PP2A activation by PTPA, an ATP-dependent activation chaperone.
Not available
S-EPMC3915903 | biostudies-literature
UnknownPTPA variants and impaired PP2A activity in early-onset parkinsonism with intellectual disability.
Not available
S-EPMC10115167 | biostudies-literature
UnknownUBE3A-mediated PTPA ubiquitination and degradation regulate PP2A activity and dendritic spine morphology.
Not available
S-EPMC6589679 | biostudies-literature
UnknownPtpA protein from Mycobacterium avium subsp. paratuberculosis as a potential marker of rheumatoid arthritis in humans.
Not available
S-EPMC11698356 | biostudies-literature
UnknownNew potential eukaryotic substrates of the mycobacterial protein tyrosine phosphatase PtpA: hints of a bacterial modulation of macrophage bioenergetics state.
Not available
S-EPMC5390082 | biostudies-literature
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