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MetabolomicsPu-erh tea and theabrownin ameliorate metabolic syndrome in mice via potential microbiota-gut-liver-brain interactions
Metabolic syndrome (MS) is a common metabolic disorder characterized by obesity, insulin resistance, cardiovascular disease and gut microbiota dysbiosis. Pu-erh tea and its ingredient theabrownin have known functions on the reduction of body weight gain and fat accumulation. However, few studies sys...
2024-09-25 | MTBLS2594 | MetaboLights
MetabolomicsTheabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism
Pu-erh tea displays cholesterol-lowering properties, but the underlying mechanism has not been elucidated. Theabrownin is one of the most active and abundant pigments in Pu-erh tea. Here, we show that theabrownin alters the gut microbiota in mice and humans, predominantly suppressing microbes associ...
2021-11-18 | MTBLS1259 | MetaboLights
TranscriptomicsMacrophage-specific gene functions in Spi1-directed innate immunity
The Spi1/ Pu.1 transcription factor plays a crucial role in myeloid cell development across many species. Several Spi1 target genes have been identified so far, yet the Spi1-dependent gene group remains largely unknown. To identify novel genes downstream of Spi1 we employed a microarray strategy usi...
ORGANISM(S): Danio rerio 
2010-04-30 | E-GEOD-19206 | biostudies-arrayexpress
UnknownEffects of L-type Calcium Channel Antagonists Verapamil and Diltiazem on fKv1.4ΔN Currents in Xenopus oocytes.
Not available
S-EPMC3920693 | biostudies-literature
ProteomicsRedox proteomics in NO-mediated protection on hypoxic cardiomyocyte
We developed a mass spectrometry (MS)-based quantitative approach using a set of novel iodoacetyl-based cysteine-reactive isobaric tags (iodoTMT) endowed with unique irreversible Cys-reactivities to differentially quantify the multiple redox-modified forms of a Cys site in the original cellular cont...
ORGANISM(S): Rattus norvegicus (Rat) 
2016-06-27 | PXD000274 | Pride
S-nitrosylation Mass spectrometry Hypoxia Redox cysteine modifications Redox-proteomics 
UnknownChlorinated Benzo[1,2-b:4,5-c']dithiophene-4,8-dione Polymer Donor: A Small Atom Makes a Big Difference.
Not available
S-EPMC7887605 | biostudies-literature
UnknownThe Bidirectional Relationship between Weight Gain and Cognitive Function in First-Episode Schizophrenia: A Longitudinal Study in China.
Not available
S-EPMC11048552 | biostudies-literature
UnknownEmergence of community-acquired adenovirus type 55 as a cause of community-onset pneumonia.
Not available
S-EPMC7094559 | biostudies-literature
UnknownRoles of p53 Family Structure and Function in Non-Canonical Response Element Binding and Activation.
Not available
S-EPMC6696488 | biostudies-literature
UnknownVitamin D3 improved hypoxia-induced lung injury by inhibiting the complement and coagulation cascade and autophagy pathway.
Not available
S-EPMC10759436 | biostudies-literature
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