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UnknownBody Mass Index Is Prognostic in Metastatic Colorectal Cancer: Pooled Analysis of Patients From First-Line Clinical Trials in the ARCAD Database.
Not available
S-EPMC5070548 | biostudies-literature
TranscriptomicsChromosomal copy number aberrations in colorectal metastases resemble their primary counterparts and differences are typically non-recurrent.
Background & Aims: The metastatic process is complex and remains a major obstacle in the management of colorectal cancer (CRC). To gain a better insight into the biologic events driving the metastatic process we investigated genomic aberrations in a large cohort of matched CRC primaries and distant ...
ORGANISM(S): Homo sapiens 
2014-02-10 | E-GEOD-38479 | biostudies-arrayexpress
UnknownPhase III randomized clinical trial comparing tremelimumab with standard-of-care chemotherapy in patients with advanced melanoma.
Not available
S-EPMC4878048 | biostudies-literature
UnknownThe soil-borne white root rot pathogen Rosellinia necatrix expresses antimicrobial proteins during host colonization.
Not available
S-EPMC10796067 | biostudies-literature
UnknownThe CAIRO4 study: the role of surgery of the primary tumour with few or absent symptoms in patients with synchronous unresectable metastases of colorectal cancer--a randomized phase III study of the Dutch Colorectal Cancer Group (DCCG).
Not available
S-EPMC4196118 | biostudies-literature
TranscriptomicsS mansoni infection B cell comparison
The helminth Schistosoma Mansoni is known to generate a regulatory B cell population that can suppress in multiple murine experimental models. Microarray comparison allows for a greater understanding as to how these cells are generated and their implications in immune regulation.
ORGANISM(S): Mus musculus 
2014-03-28 | E-MTAB-2100 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of enforced HOXA1 expression in melanoma cell line (SkMel30)
We recently reported an oncogenomics-guided screening approach designed to identify genetic drivers of early stage melanoma metastasis, and in this study we functionally validate the top-scoring candidate, homeobox transcription factor A1 (HOXA1), by demonstrating HOXA1 robust effects on melanoma ce...
ORGANISM(S): Homo sapiens 
2013-01-01 | E-GEOD-40422 | biostudies-arrayexpress
UnknownTreatment strategies in colorectal cancer patients with initially unresectable liver-only metastases, a study protocol of the randomised phase 3 CAIRO5 study of the Dutch Colorectal Cancer Group (DCCG).
Not available
S-EPMC4445284 | biostudies-literature
TranscriptomicsNon-targeted effects of low dose ionizing radiation act via TGF-beta to promote mammary carcinogenesis
This is a genome-wide approach to identifying genes persistently induced in the mouse mammary gland by acute whole body low dose ionizing radiation (10cGy), 1 and 4 weeks after exposure. Gene expression that is modified under these parameters were compared between Tgfb1 wild type and heterozygote li...
ORGANISM(S): Mus musculus 
2010-03-07 | E-GEOD-18216 | biostudies-arrayexpress
UnknownUGT1A1*28 genotype and irinotecan dosage in patients with metastatic colorectal cancer: a Dutch Colorectal Cancer Group study.
Not available
S-EPMC2480976 | biostudies-literature
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