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UnknownGood response to PAH-targeted drugs in a PVOD patient carrying Biallelic EIF2AK4 mutation.
Not available
S-EPMC6167821 | biostudies-literature
UnknownRapid disease progress in a PVOD patient carrying a novel EIF2AK4 mutation: a case report.
Not available
S-EPMC7336641 | biostudies-literature
UnknownSendai Virus Induces Persistent Olfactory Dysfunction in a Murine Model of PVOD via Effects on Apoptosis, Cell Proliferation, and Response to Odorants.
Not available
S-EPMC4948916 | biostudies-literature
ProteomicsEssential role of Protein kinase R in the pathogenesis of pulmonary veno-occlusive disease
Pulmonary veno-occlusive disease (PVOD) is a rare and severe form of pulmonary arterial hypertension, characterized by progressive obstruction of small pulmonary vessels and a lack of effective therapeutic options. Our previous research, utilizing a mitomycin C (MMC)-induced rat model, demonstrated ...
ORGANISM(S): Mus musculus (Mouse) 
2025-08-11 | PXD066782 | Pride
Protein kinase r Proteomics Pvod 
TranscriptomicsPatient-specific and Gene-corrected Induced Pluripotent Stem Cell-derived Endothelial Cells Elucidate Single-cell Phenotype of Pulmonary Veno-occlusive Disease
PVOD is a rare form of pulmonary hypertension characterized by the preferential remodeling of the pulmonary venules. Hereditary PVOD is caused by biallelic variants of the EIF2AK4 gene. Three PVOD patients who carried the compound heterozygous variants of EIF2AK4 and two healthy controls were recrui...
ORGANISM(S): Homo sapiens 
2022-10-21 | GSE215978 | GEO
GenomicsDifferential Expression Profile of MicroRNAs and Tight Junction in Lung Tissue of Rat with Mitomycin-C Induced Pulmonary Veno-Occlusive Disease
Pulmonary veno-occlusive disease (PVOD) is characterized by increased pulmonary vascular resistance. Currently, there is a lack of effective treatment. It is of great significance to explore molecular targets for treatment of the disease. This study investigated the differentially expressed profile ...
ORGANISM(S): Rattus norvegicus 
2021-11-30 | GSE189080 | GEO
UnknownPatient-specific and gene-corrected induced pluripotent stem cell-derived endothelial cells elucidate single-cell phenotype of pulmonary veno-occlusive disease.
Not available
S-EPMC9768576 | biostudies-literature
GenomicsPatient-specific and Gene-corrected Induced Pluripotent Stem Cell-derived Endothelial Cells Elucidate Single-cell Phenotype of Pulmonary Veno-occlusive Disease
Patient-specific and Gene-corrected Induced Pluripotent Stem Cell-derived Endothelial Cells Elucidate Single-cell Phenotype of Pulmonary Veno-occlusive Disease
PRJNA891628 | ENA
TranscriptomicsTranscription profiling of human peripheral blood mononuclear (PBMC) cells in pulmonary arterial hypertension
Microarray analysis of peripheral blood mononuclear (PBMC) cells in pulmonary arterial hypertension.
ORGANISM(S): Homo sapiens 
2007-09-21 | E-GEOD-703 | biostudies-arrayexpress
UnknownComparison of pulsed vacuum and ultrasound osmotic dehydration on drying of Chinese ginger (Zingiber officinale Roscoe): Drying characteristics, antioxidant capacity, and volatile profiles.
Not available
S-EPMC6694637 | biostudies-literature
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