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ProteomicsA variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes
Transcriptional regulation by chromatin is a highly dynamic process directed through the recruitment and coordinated action of epigenetic modifiers and readers of these modifications. Using an unbiased proteomic approach to find interactors of H3K36me3, a modification enriched on active chromatin, w...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2018-07-19 | PXD010445 | Pride
Nurd Pwwp2a/b Hdac 
GenomicsNascent transcription of E14, PWWP2AKO, and PWWP2A/B DKO
Nascent transcription of E14, PWWP2AKO, and PWWP2A/B DKO
PRJNA439319 | ENA
TranscriptomicsNascent transcription of E14, PWWP2AKO, and PWWP2A/B DKO
Transcriptional regulation by chromatin is a highly dynamic process directed through the recruitment and coordinated action of epigenetic modifiers and readers of these modifications. Using an unbiased proteomic approach to find interactors of H3K36me3, a modification enriched on active chromatin, h...
ORGANISM(S): Mus musculus 
2018-07-20 | GSE112112 | GEO
UnknownA variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes.
Not available
S-EPMC6143588 | biostudies-literature
GenomicsA variant NuRD complex containing PWWP2A/B excludes MBD2/3 and directs HDAC activity to regulate histone acetylation and RNA Pol II dynamics
A variant NuRD complex containing PWWP2A/B excludes MBD2/3 and directs HDAC activity to regulate histone acetylation and RNA Pol II dynamics
PRJNA439320 | ENA
GenomicsA variant NuRD complex containing PWWP2A/B excludes MBD2/3 and directs HDAC activity to regulate histone acetylation and RNA Pol II dynamics
Transcriptional regulation by chromatin is a highly dynamic process directed through the recruitment and coordinated action of epigenetic modifiers and readers of these modifications. Using an unbiased proteomic approach to find interactors of H3K36me3, a modification enriched on active chromatin, h...
ORGANISM(S): Mus musculus 
2018-07-20 | GSE112113 | GEO
TranscriptomicsPWWP2A variant NuRD complex represses intragenic spurious transcription initiation
H3 trimethylation at K36 deposited over the body of actively transcribed gene, is recognized by readers to modulate the epigenetic states, such as DNA methylation and histone deacetylation, to ensure the proper gene transcription. PWWP2A was identified as the reading component of variant NuRD comple...
ORGANISM(S): Mus musculus 
2020-09-15 | GSE148382 | GEO
UnknownThe PWWP2A Histone Deacetylase Complex Represses Intragenic Spurious Transcription Initiation in mESCs.
Not available
S-EPMC7670215 | biostudies-literature
GenomicsA variant NuRD complex containing PWWP2A/B excludes MBD2/3 and directs HDAC activity to regulate histone acetylation and RNA Pol II dynamics at active genes
A variant NuRD complex containing PWWP2A/B excludes MBD2/3 and directs HDAC activity to regulate histone acetylation and RNA Pol II dynamics at active genes
PRJNA439314 | ENA
GenomicsPWWP2A variant NuRD complex represses intragenic spurious transcription initiation
PWWP2A variant NuRD complex represses intragenic spurious transcription initiation
PRJNA624108 | ENA
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