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TranscriptomicsRNA Sequencing Quantitative Analysis of cell lines derived from tumours from two mouse models of human osteosarcoma that recapitulate clinically distinct human osteosarcoma subtypes.
Purpose: Osteosarcoma (OS) is the most common primary bone malignancy. OS consists of several subtypes including fibroblastic, osteoblastic and chondroblastic OS. We have developed genetically engineered mouse models of human OS that recapitulate two distinct subtypes, fibroblastic (Osx-CreLox p53-/...
ORGANISM(S): Mus musculus 
2015-07-06 | E-GEOD-58916 | biostudies-arrayexpress
UnknownNutrient limitation shapes functional traits of mycorrhizal fungi and phosphorus-cycling bacteria across an elevation gradient.
Not available
S-EPMC12817948 | biostudies-literature
TranscriptomicsWhole blood gene expression profiles distinguish clinical phenotypes of venous thromboembolism [Set1]
Recurrent venous thromboembolism (VTE) occurs infrequently following a provoked event but occurs in up to 30% of individuals following an initial unprovoked event. We studied 134 patients with VTE separated into 3 groups: (1) ‘low-risk’ patients had ≥1 provoked VTE; (2) ‘moderate-risk’ pa...
ORGANISM(S): Homo sapiens 
2015-11-23 | E-GEOD-48000 | biostudies-arrayexpress
UnknownVisualizing group II intron catalysis through the stages of splicing.
Not available
S-EPMC3628766 | biostudies-literature
UnknownCrystal structure of group II intron domain 1 reveals a template for RNA assembly.
Not available
S-EPMC4651773 | biostudies-literature
TranscriptomicsADAR1-mediated A-to-I RNA editing is essential for erythropoiesis [RNA-seq]
Purpose: RNA editing by ADAR1 is essential for hematopoietic development. The goals of this study were firstly, to identify ADAR1-specific RNA-editing sites by indentifying A-to-I (G) RNA editing sites in wild type mice that were not edited or reduced in editing frequency in ADAR1 deficient murine e...
ORGANISM(S): Mus musculus 
2016-07-24 | E-GEOD-71042 | biostudies-arrayexpress
UnknownAMIGOS III: pseudo-torsion angle visualization and motif-based structure comparison of nucleic acids.
Not available
S-EPMC9113296 | biostudies-literature
UnknownHomozygous deletion in MICU1 presenting with fatigue and lethargy in childhood.
Not available
S-EPMC4830195 | biostudies-literature
UnknownThe SMN complex drives structural changes in human snRNAs to enable snRNP assembly.
Not available
S-EPMC10584915 | biostudies-literature
UnknownVisualizing the ai5γ group IIB intron.
Not available
S-EPMC3919574 | biostudies-literature
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