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The overconsumption of carbohydrates induces oxidative stress and lipid accumulation in the liver, which can be alleviated by modulation of intestinal microbiota; however, the underlying mechanism remains unclear. Here, we demonstrated that a strain affiliated with Lactobacillus plantarum (de...
2024-01-16 | MTBLS4262 | MetaboLights
Transcripitonal profiling of Escherichia coli K-12 comparing luxS mutant LW12 with wild type W3110 One-condition experiment, luxS mutant LW12 vs. wild type W3110
ORGANISM(S): Escherichia coli 
The physiological role of the spliced form of X-box-binding protein 1 (XBP1s), a key transcription factor of the endoplasmic reticulum (ER) stress response, in adipose tissue remains largely unknown. Here we show that overexpression of XBP1s promotes adiponectin multimerization in adipocytes, thereb...
ORGANISM(S): Mus musculus 
The liver is the central organ critically regulating the balance of the metabolically potent yet toxic bile acids in the body. While genomic association studies have pointed to hepatic Sel1L – a critical component of mammalian Hrd1 ER-associated degradation (ERAD) machinery – as an influencer of ser...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD035243 | Pride
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