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TranscriptomicsTranscription profiling of human hematopoietic stem cells engrafted into fetal goats
Robust human-goat chimerism was achieved by transplanting human CD34+Lin- cord blood cells into fetal goats. We observed a broad distribution of GFP-marked human cells in non-hematopoietic organs including kidney, muscle, lung, and heart of transplant goats. Various marker techniques indicated that...
ORGANISM(S): Homo sapiens 
2007-07-19 | E-GEOD-1801 | biostudies-arrayexpress
TranscriptomicsLymphoid Priming in Human Bone Marrow Begins Prior to CD10 Expression with Up-Regulation of L-selectin
Studies of adult human hematopoiesis have until now relied on the expression of CD10 to define lymphoid commitment. We report a novel lymphoid-primed population in human bone marrow that is generated from hematopoietic stem cells (HSC) prior to the onset of CD10 expression and B cell commitment, and...
ORGANISM(S): Homo sapiens 
2012-08-14 | E-GEOD-35685 | biostudies-arrayexpress
ProteomicsPolygonum perfoliatum L. ameliorates NAFLD by promoting PPARs/CPT1A/CPT2-mediated fatty acid β-oxidation
We performed a label-free quantitative proteomic profiling to determine the effect of Polygonum perfoliatum L. treated the proteomics profile of liver tissue and identified activated PPARs/CPT1A/CPT2-mediated hepatic fatty acid β oxidation process was significantly altered
ORGANISM(S): Mus Musculus 
2024-02-05 | PXD033219 |
UnknownPredictive effects of bilirubin on response of colorectal cancer to irinotecan-based chemotherapy.
Not available
S-EPMC4837442 | biostudies-literature
UnknownMechanism of Abelmoschus manihot L. in the Treatment of Contrast-Induced Nephropathy on the Basis of Network Pharmacology Analysis.
Not available
S-EPMC10479589 | biostudies-literature
UnknownEffect of later cord clamping on umbilical cord blood gas in term neonates of diabetic mothers: a randomized clinical trial.
Not available
S-EPMC8886805 | biostudies-literature
UnknownInhibitory effect of eugenol on seed germination and pre-harvest sprouting of hybrid rice (Oryza sativa L.).
Not available
S-EPMC5509651 | biostudies-literature
MetabolomicsUPLC-MS-Based Serum Metabolic Profiling Reveals Potential Biomarkers for Predicting Propofol Responsiveness in Females

Although previous studies have shown that certain factors interfere with the sensitivity of propofol, the mechanisms for interindividual variability in response to propofol remain unclear. This study aimed to screen the metabolites to predict patients' sensitivity to propofol and to identify meta...

2021-09-29 | MTBLS2311 | MetaboLights
TranscriptomicsscRNA-seq CRISPR screening of human posterior brain organoids
We used a pooled, multiplexed CRISPR/Cas9 gene knock-out (KO) experiment with single-cell transcriptomic readout to perturb and validate selected TF regulomes . We designed gRNAs and generated a pooled lentiviral library targeting 12 TFs with specific midbrain or hindbrain expression or high regulat...
ORGANISM(S): Homo sapiens 
2026-03-17 | E-MTAB-15826 | biostudies-arrayexpress
UnknownWTX-L/β-arrestin2/LCN2 axis controls vulnerability to ferroptosis in gastric cancer.
Not available
S-EPMC11919608 | biostudies-literature
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