Sort   by:  
 Page size 
ProteomicsA multi-species spike-in sample set for performance evaluation of label-free proteomics quantification
When evaluating the quantitative performance of label-free proteomics method(s), samples with known compositions are necessary to define key parameters such as reproducibility, missing data levels, accuracy, precision, as well as sensitivity/specificity for biomarker discovery. Here, we provide a ca...
ORGANISM(S): Homo sapiens (Human) Escherichia coli Saccharomyces cerevisiae (Baker's yeast) 
2022-01-06 | PXD030780 | Pride
Performance evaluation Label-free quantification Ionstar 
ProteomicsMulti-compartment quantitative proteomics revealing potential mechanisms underlying the treatment effects of mesenchymal-derived extracellular vesicles in a monkey model of cortical injury
Cortical injury frequently causes motor dysfunction, significantly impairing activities of daily living, and currently, there are no effective therapeutic options available. Previous studies demonstrated that intravenous infusion of mesenchymal stromal cell-derived extracellular vesicles (MSC-EVs) e...
ORGANISM(S): Macaca mulatta (Rhesus macaque) 
2026-06-15 | PXD059286 | Pride
Mesenchymal stromal cell-derived extracellular vesicles Cortical injury Rhesus macaque Brain tissue Plasma Csf Lc-ms/ms 
ProteomicsBioID study of the PHB2 interactome in Schwann cells and how it changes depending on neuronal signals
Schwann cells are critical for the proper development and function of the peripheral nervous system, where they form a collaborative relationship with axons. Past studies highlighted that a pair of proteins called the prohibitins play major roles in Schwann cell biology. Prohibitins are ubiquitously...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-09-02 | PXD054241 | Pride
Interactome 
ProteomicsLabel-free proteomics quantification of pancreatic ductal adenocarcinoma patient-derived xenografts with treatment combining Gemcitabine and nab-Paclitaxel
Tumor-stroma interactions are critical in pancreatic ductal adenocarcinoma (PDAC) progression and therapeutics. Patient-derived xenograft (PDX) models faithfully recapitulate tumor-stroma interactions in PDAC, but conventional antibody-based immunoassay is largely inadequate to resolve or quantify t...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2023-07-05 | PXD042267 | Pride
Lc-ms/ms patient-derived xenografts species-deconvolved proteomics 
ProteomicsRaw data of 218 FFPE tissue proteomes containing 144 tissue samples from seven organs of fatal VID-19 cases and 74 control specimens from 56 non-COVID-19 individuals
144 tissue samples from postmortem lung, liver, kidney, heart, spleen, testis and thyroid collected from 19 COVID-19 cases and 74 control specimens from 56 non-COVID-19 individuals were analyzed by PCT and TMT 16-plex based proteomics.
ORGANISM(S): Homo Sapiens 
2020-12-11 | PXD022775 |
Sort   by:  
 Page size