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ProteomicsDisome-seq reveals sequence-mediated coupling of translational pauses and protein structures
The regulation of translation elongation plays a vital role in protein folding; an adequate translational pause provides time and cellular environments for the co-translational folding of nascent peptides. However, the genomic landscape, sequence determinants, and molecular consequences of translati...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-12-10 | PXD015271 | Pride
Silac Saccharomyces cerevisiae 
ProteomicsQuantitative proteomics of Col and AtPABs mutant
To determine if the difference in AtPAB-binding efficiency affects protein levels, we performed the Tandem Mass Tag (TMT)-based quantitative proteomics on the two-week old seedlings of Col and the mut, respectively.
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-10-11 | PXD014071 | Pride
Poly(a)-binding proteins  binding efficiency  translationa  arabidopsis 
ProteomicsHuman Plasma Proteome with Three-dimensional Strategies by Highresolution Quadrupole Orbitrap Mass Spectrometry
Five three-dimensional strategies combining HAP depletion (the 1st dimension) and protein fractionation (the 2nd dimension), followed by LC-MS/MS analysis (the 3rd dimension) were developed and compared for human plasma proteome profiling. Pros and cons of the five strategies are discussed for two i...
ORGANISM(S): Homo Sapiens 
2017-06-20 | PXD008441 |
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