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ProteomicsCell Data-Indenpendent acquisition LC-MS/MS
In this work, a microwell-chip was prepared and modified. The microwell-chip was used for extraction of metabolites and subsequent protein digestion. Next, direct electrospray ionization mass spectrometry (ESI-MS) was adopted for metabolome identification and a data independent acquisition (DIA)-MS ...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2021-11-08 | PXD025634 | Pride
Dia Cell Lc-ms/ms 
UnknownRegulation of CARD8 expression by ANRIL and association of CARD8 single nucleotide polymorphism rs2043211 (p.C10X) with ischemic stroke.
Not available
S-EPMC3962686 | biostudies-literature
ProteomicsNafamostat Mesilate Improves Sepsis Outcomes by Modulating Complement and Coagulation Pathways
Supporting data for: Nafamostat Mesilate Improves Sepsis Outcomes by Modulating Complement and Coagulation Pathways
ORGANISM(S): Homo Sapiens 
2026-02-24 | PXD074871 |
ProteomicsStructure-guided development of chemically tailored peptide binders of RNF43/ZNRF3 to enable versatile design of membrane protein-targeting PROTACs
Targeted membrane protein degradation using cell surface E3 ligases RNF43/ZNRF3 via proteolysis targeting chimeras (PROTACs) represents an effective strategy for treating membrane drug targets that cannot be fully inhibited using traditional inhibitors. Several ingenious chimeras have been developed...
ORGANISM(S): Homo Sapiens 
2025-03-04 | PXD061425 |
ProteomicsQuantitative proteomics reveals the protective effects of Yinchenzhufu decoction against cholestatic liver fibrosis in mice by inhibiting PDGFRβ/PI3K/AKT pathway
Yinchenzhufu decoction (YCZFD) is a traditional Chinese medicine formula with hepatoprotective effects. In this study, the protective effects of YCZFD against cholestatic liver fibrosis and its mechanisms of action were evaluated in a mouse model of 3,5-diethoxycarbonyl-1,4-dihydro-collidine (DDC)-i...
ORGANISM(S): Mus Musculus 
2023-10-13 | PXD046101 |
ProteomicsShiga toxin 2a induces mitochondrial damage, mitophagy and apoptosis via the interaction of Tom20 in Caco-2 cells
Shiga toxin type 2 (Stx2) is the main virulence factor produced by Stx-producing Escherichia coli (STEC) responsible for hemorrhagic colitis and the life-threatening sequela hemolytic uremic syndrome.
ORGANISM(S): Homo Sapiens 
2022-11-21 | PXD038256 |
ProteomicsSerum proteomics of individuals with MASLD under resistance starch intervention
Searching for baseline proteins that contribute to the individual response to RS intervention
ORGANISM(S): Homo Sapiens 
2025-09-24 | PXD068798 |
UnknownComparison of the Oral Calcimimetics Evocalcet and Cinacalcet in East Asian Patients on Hemodialysis with Secondary Hyperparathyroidism.
Not available
S-EPMC10658267 | biostudies-literature
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