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UnknownCoronavirus disease 2019 in pregnant women: a report based on 116 cases.

Background

The coronavirus disease 2019, caused by severe acute respiratory syndrome coronavirus 2, is a global public health emergency. Data on the effect of coronavirus disease 2019 in pregnancy are limited to small case series.

Objective

To evaluate the clinical characteristics and...
S-EPMC7177142 | biostudies-literature
MetabolomicsEffects of Yulin Tong Bu formula on modulating gut microbiota and fecal metabolite interactions in mice with polycystic ovary syndrome

BACKGROUND: Polycystic ovarian syndrome (PCOS) is a common endocrine disorder characterized by hyperandrogenism, ovarian dysfunction and polycystic ovarian morphology. Gut microbiota dysbiosis and metabolite are associated with PCOS clinical parameters. Yulin Tong Bu formula (YLT...

2023-02-02 | MTBLS6736 | MetaboLights
UnknownPrognostic Significance of p16 and Its Relationship with Human Papillomavirus Status in Patients with Penile Squamous Cell Carcinoma: Results of 5 Years Follow-Up.
Penile Squamous Cell Carcinoma (PSCC) is associated with high-risk human papillomavirus (HR-HPV). The immunohistochemical (IHC) test for p16INK4a (p16) is highly correlated with HR-HPV expression in other SCCs. To investigate whether the expression of p16 IHC or HR-HPV is associated with ...
S-EPMC9775956 | biostudies-literature
UnknownSpecies packing and the latitudinal gradient in beta-diversity.
The decline in species richness at higher latitudes is among the most fundamental patterns in ecology. Whether changes in species composition across space (beta-diversity) contribute to this gradient of overall species richness (gamma-diversity) remains hotly debated. Previous studies that failed to...
S-EPMC8059527 | biostudies-literature
UnknownA village doctor-led mobile health intervention for cardiovascular risk reduction in rural China: cluster randomised controlled trial.

Objective

To assess the effectiveness of a village doctor-led mobile health intervention on cardiovascular risk reduction among residents in rural China.

Design

Cluster randomised controlled trial.

Setting

127 villages from five provinces and autonomous regions in China.

Par...

S-EPMC12107442 | biostudies-literature
UnknownWhole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children With Asthma.

Background

Asthma is a common respiratory disorder with a highly heterogeneous nature that remains poorly understood. The objective was to use whole genome sequencing (WGS) data to identify regions of common genetic variation contributing to lung function in individuals with a diagnosis of a...
S-EPMC6904857 | biostudies-literature
UnknownJinlida for Diabetes Prevention in Impaired Glucose Tolerance and Multiple Metabolic Abnormalities: The FOCUS Randomized Clinical Trial.

Importance

Previous studies have shown that Jinlida (JLD) granules, an approved treatment for type 2 diabetes in China, can reduce blood glucose level, reduce glycated hemoglobin (HbA1c), and improve insulin resistance in people with type 2 diabetes.

Objective

To evaluate the effect o...
S-EPMC11148787 | biostudies-literature
UnknownGenetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci.
Exfoliation syndrome (XFS) is the most common known risk factor for secondary glaucoma and a major cause of blindness worldwide. Variants in two genes, LOXL1 and CACNA1A, have previously been associated with XFS. To further elucidate the genetic basis of XFS, we collected a global sample of XFS case...
S-EPMC6685441 | biostudies-literature
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