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The interplay between cancer cells and microenvironment can influence treatment response and plays a key role in the emergence of drug resistance. Rapidly acquired resistance prevents proteasome inhibitors (PIs) therapies from achieving stable and complete responses. Investigating the underlying mec...
ORGANISM(S): Homo sapiens (Human) 
2020-05-27 | PXD014711 | Pride
Exosomes in the microenvironment play key roles in cellular signal transduction. The biological function of exosomes in cancer metastasis and progression, however, is still unknown.We used quantitative proteomics in this study to decipher the proteome of cellular exosomes derived from highly/lowly m...
ORGANISM(S): Homo sapiens (Human) 
2019-06-17 | PXD013419 | Pride

INTRODUCTION Alzheimer's disease is a prevalent disease with a heavy global burden and is suggested to be a metabolic disease in the brain in recent years. The metabolome is considered to be the most promising phenotype which reflects changes in genetic, transcript, and protein ...

2024-01-11 | MTBLS8662 | MetaboLights
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