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TranscriptomicsHuman hepatic stellate cell line LX-2 activated under acidic culture condition
We found that the number of tumor-infiltrating myofibroblasts was positively correlated to tumor acidification status in hepatocellular carcinoma (HCC). Hepatic stellate cells (HSCs), the predominant precursors of liver myofibroblasts, were activated and transdifferentiated into myofibroblasts under...
ORGANISM(S): Homo sapiens 
2013-07-29 | E-GEOD-49301 | biostudies-arrayexpress
TranscriptomicsEffect of CTHRC1 knockdown on gene expression of HCCLM3 cells
Collagen triple helix repeat containing 1 (CTHRC1) has been found to be up-regulated in many human solid tumors. In this study, we investigated the changes of gene expression by comparing CTHRC1-siRNA and Scramble-siRNA control in hepatocellular carcinoma cell line HCCLM3, which has high expression ...
ORGANISM(S): Homo sapiens 
2012-04-22 | E-GEOD-37208 | biostudies-arrayexpress
ProteomicsThermostable neurotoxins in processed scorpion medicinal material underlie its pharmaceutical basis in traditional Chinese medicine
Our work describes the first "map" of functionally active scorpion toxins in processed scorpion medicinal material and provides valuable information for unveiling the pharmaceutical basis for the “combat poison with poison to cure diseases” strategy in traditional Chinese medicine.
ORGANISM(S): Mesobuthus Martensii 
PXD012392 |
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