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ProteomicsCell Data-Indenpendent acquisition LC-MS/MS
In this work, a microwell-chip was prepared and modified. The microwell-chip was used for extraction of metabolites and subsequent protein digestion. Next, direct electrospray ionization mass spectrometry (ESI-MS) was adopted for metabolome identification and a data independent acquisition (DIA)-MS ...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2021-11-08 | PXD025634 | Pride
Dia Cell Lc-ms/ms 
UnknownReference gene selection for real-time quantitative PCR analysis on ovarian cryopreservation by vitrification in mice.
Not available
S-EPMC4554379 | biostudies-literature
MetabolomicsClinical efficacy of Yiqi Yangxue formula on knee osteoarthritis and unraveling therapeutic mechanism through plasma metabolites in rats.

OBJECTIVE: To observe the clinical efficacy and safety of Yiqi Yangxue formula (YQYXF) on knee osteoarthritis (KOA), and to explore the underlying therapeutic mechanism of YQYXF through endogenous differential metabolites and their related metabolic pathways.

METHOD...

2024-03-25 | MTBLS5667 | MetaboLights
ProteomicsDeep Profiling of the Human Plasma Proteome with Surface-Functionalized Molybdenum Disulfide Nanomaterials
Here, we report the synthesis and characterization of surface-functionalized magnetic molybdenum disulfide (MoS2) for the large-scale enrichment of low abundant plasma proteins and deep profiling by mass spectrometry.
ORGANISM(S): Homo Sapiens Escherichia Coli 
2022-09-15 | PXD036756 |
ProteomicsTandem Enrichment and Simultaneous Profeling
Tandem Enrichment and Simultaneous Profeling of N-glycopeptides and phosphopeptides
ORGANISM(S): Homo Sapiens 
PXD033282 |
ProteomicsPUMILIO Proteins in Colorectal Cancer: Tumor Growth Promoting Function and Potential as Therapeutic Targets
We employ Mass spectrum to investigate proteome of Pum1-Knockout, Pum2-Knockout and WT conditions in human colorectal cancer cell line Hct116. Overall design: In order to investigate whether Pum1 and Pum2 regulate their targets at their protein levels, we used Pum1-Knockout, Pum2-Knockout and WT Hct...
ORGANISM(S): Homo Sapiens 
2021-07-23 | PXD027513 |
ProteomicsProteomics analysis reveals novel insights into the mechanism of hepatotoxicity induced by Tripterygium Wilfordii multiglycoside in mice
Tripterygium wilfordii multiglycoside (GTW), extracted and purified from the peeled roots of Tripterygium wilfordii Hook.f. (TwHF), is a well-known traditional Chinese medicine and applied to various autoimmune diseases clinically. However, it has been reported to cause severe liver injury. At prese...
ORGANISM(S): Mus Musculus 
2022-11-10 | PXD038084 |
ProteomicsProteomics-based mechanistic investigation of Staphylococcus aureus inactivation by pulsed electric field
The Staphylococcus aureus strain was cultured in LB medium at 150 rpm and 37 ℃ to a final optical density (OD) of 1.0 at 600 n m. Subsequently, 1 m L of the culture broth was collected and centrifuged at 8000 rpm, 4 ℃ for 2 min. The cell pellet was re-suspended in 2 m L of ice-cold 0.1% (w/v) bacter...
ORGANISM(S): Staphylococcus Aureus 
PXD026761 |
ProteomicsProteomics-based mechanistic investigation of Escherichia coli inactivation by pulsed electric field
mechanistic investigation of Escherichia coli inactivation
ORGANISM(S): Escherichia Coli Vdp 
2019-06-25 | PXD014365 |
ProteomicsInteraction partners with NOP2/Sun RNA methyltransferase 2 (NSUN2) in gallbladder carcinoma
Proteins interacting with NSUN2 in gallbladder carcinoma (NOZ cell line)
ORGANISM(S): Homo Sapiens 
2019-03-20 | PXD013152 |
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