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Leprosy is a chronic infectious disease caused by Mycobacterium leprae (M. leprae). Due to M. leprae's narrow host range and an inability to be cultured in vitro, the biological investigation of this disease has been difficult. Host genetic factors have been ...

We investigate the role of Brg1 and Olig2 during oligodendrocyte differentiation by combining gene conditional knockout and next generation sequencing technology. We generate genome-wide maps of RNA polymerase II (RPolII), Brg1 (Smarca4), Olig2 and histone modifications in primary rat oligodendrocyt...
ORGANISM(S): Rattus norvegicus 
Spinal cord mRNA profiles of 14-day-old control (Brg1c/+;Olig1-Cre) and Smarca4/Brg1 conditional knockout (Brg1c/c;Olig1-Cre) mice were generated by RNA-seq. Differential expressed genes are identified using Cuffdiff and validated with qPCR. Spinal cord mRNA profiles of 14-day old control and Brg1c/...
ORGANISM(S): Mus musculus 
We used proteomics to compare the differential protein expression between adult and metacercariae stage of Metorchis orientalis. Three biological replicates were set up at each stage for protein analysis using Nano HPLC.
ORGANISM(S): Metorchis Orientalis 
2021-10-08 | PXD029022 |
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