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TranscriptomicsDirect reprogramming of mouse fibroblasts into cardiomyocytes with chemical cocktails
The direct conversion, or trans-differentiation, of non-cardiac cells into cardiomyocytes by forced expression of transcription factors and microRNAs provide promising ways of cardiac regeneration. However, genetic manipulations are still not desirable in real clinical applications. we report the ge...
ORGANISM(S): Mus musculus 
2015-08-23 | E-GEOD-69924 | biostudies-arrayexpress
ProteomicsThe H3K4 methyltransferase KMT2D is an essential cofactor for GATA1 at erythroid gene enhancers
Gene expression during cellular differentiation is coordinated by combinatorial interactions between transcription factors (TFs) and cofactors at promoters and enhancers. The “master TF” GATA1 coordinates gene transcription in a subset of hematopoietic lineages, including erythroid, megakaryocytic, ...
ORGANISM(S): Homo sapiens (Human) 
2026-04-10 | PXD076443 | Pride
Kmt2d  gata1  enhancer  transcription regulation  hematopoiesis  erythropoiesis  epigenetics 
UnknownLocalized DNA tetrahedrons assisted catalytic hairpin assembly for the rapid and sensitive profiling of small extracellular vesicle-associated microRNAs.
Not available
S-EPMC9714172 | biostudies-literature
MetabolomicsExogenous L-Alanine promotes phagocytosis multidrug-resistant bacterial pathogens (L-Alanine-treated macrophage metabolomics)

Multidrug-resistant bacteria present a major threat to public health. Therefore, new drugs or approaches are urgently needed to manage and mitigate this threat. Here, we screen the molecular candidates that allow the survival of mice upon Vibrio parahaemolyticus infection by integrated p...

2024-09-26 | MTBLS7986 | MetaboLights
ProteomicsMitochondrial LC-MS/MS in Hep3B cells
We sought to identify mitochondrially translocated proteins with previously unrecognized contributions to hepatocellular carcinoma (HCC), using LC-MS/MS-based proteomics analysis.
ORGANISM(S): Homo sapiens (Human) 
2024-05-21 | PXD036920 | Pride
Hep3b cells Mitochondrial Lc-ms/ms 
TranscriptomicsThe transcriptome sequencing of yak (Bos grunniens)
Deep sequencing of mRNA from 6 organs of yak (Bos grunniens) Analysis of ploy(A)+ RNA of brain,heart,liver,lung,spleen, and stomach of yak (Bos grunniens)
ORGANISM(S): Bos grunniens 
2012-05-18 | E-GEOD-33300 | biostudies-arrayexpress
Proteomics3D Mechanical Stimulation Modulates Endothelial Exosomes to Promote Fibroblast Activation
Background: Mechanical forces play a crucial role in regulating cellular communication during tissue repair, yet how mechanical stimulation modulates endothelial exosome secretion and their effects on fibroblast activation remains unclear. Methods: In this study, endothelial cells were incorporated ...
ORGANISM(S): Homo Sapiens 
2025-12-25 | PXD072415 |
UnknownUsing urban landscape pattern to understand and evaluate infectious disease risk.
Not available
S-EPMC8017915 | biostudies-literature
UnknownTherapeutic efficacy of pirfenidone and nintedanib in pulmonary fibrosis; a systematic review and meta-analysis
Not available
S-EPMC12333965 | biostudies-literature
UnknownFunctional poly(ionic liquid) with unique zwitterionic structure as efficient catalyst for the conversion of ethylene carbonate to dimethyl carbonate.
Not available
S-EPMC12755226 | biostudies-literature
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