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TranscriptomicsQuantitative analysis of wild type and MeCP2-/y mice hippocampus miRNAs using next generation sequencing
To determine whether the miRNA expression profile is altered by MeCP2, we performed Solexa-based RNA sequencing(RNA-seq) to assess global changes in the expression pattern of miRNAs caused by the loss of MeCP2 in mecp2 null (knockout[KO]) mice (Chen et al., 2001). Hippocampus miRNA profiles of 30-da...
ORGANISM(S): Mus musculus 
2016-08-08 | E-GEOD-59029 | biostudies-arrayexpress
TranscriptomicsIdentification of response genes upon neuronal activation in mouse cortical neurons
We search for developmental changes specific to humans by examining gene expression profiles in the human, chimpanzee and rhesus macaque prefrontal and cerebellar cortex. In both brain regions, developmental patterns were more evolved in humans than in chimpanzees. The major human specific genes in ...
ORGANISM(S): Mus musculus 
2012-02-02 | E-GEOD-29139 | biostudies-arrayexpress
ProteomicsEnergy-translation coupling limits yeast anaerobic growth
This study employs yeast as a model system to thoroughly investigate the differences in regulatory mechanisms under various nutrient limitation conditions, utilizing a systems biology approach integrated with techniques such as multi-omics analysis.To obtain a comprehensive quantitative landscape of...
ORGANISM(S): Staphylococcus Aureus 
PXD078963 |
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