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TranscriptomicsMechanistic information on perfluorooctanoic acid (PFOA) exposure in zebrafish (Danio rerio)
Perfluorooctanoic acid (PFOA) is one of the most used perfluorinated compounds in numerous applications and can be detected in environmental samples from around the globe. The aquatic environment is an important site for PFOA deposit. Nevertheless, the exact mode of action and its resulting toxicolo...
ORGANISM(S): Danio rerio 
2013-07-20 | E-GEOD-19908 | biostudies-arrayexpress
TranscriptomicsThyroid Hormone (TH) Controls The Remodeling Of The Pancreas And The Liver, Part B
Thyroid hormone (TH) controls the remodeling of the pancreas and the liver. TH-induces dedifferentiation of the exocrine pancreas to a progenitor state (Proc. Nat. Acad Sci. 105, 8962-8967 (2008)) and it remodels the endocrine pancreas (Dev. Biol. 328, 384-391 (2009)). The redifferentiated frog pan...
ORGANISM(S): Xenopus laevis 
2010-05-16 | E-GEOD-16017 | biostudies-arrayexpress
TranscriptomicsThyroid Hormone (TH) Controls The Remodeling Of The Pancreas And The Liver
This SuperSeries is composed of the following subset Series: GSE16017: Thyroid Hormone (TH) Controls The Remodeling Of The Pancreas And The Liver, Part B GSE16018: Thyroid Hormone (TH) Controls The Remodeling Of The Pancreas And The Liver, Part C GSE16074: Thyroid Hormone (TH) Controls The Remodelin...
ORGANISM(S): Xenopus laevis 
2010-05-16 | E-GEOD-16075 | biostudies-arrayexpress
TranscriptomicsThyroid Hormone (TH) Controls The Remodeling Of The Pancreas And The Liver, Part C
Thyroid hormone (TH) controls the remodeling of the pancreas and the liver. TH-induces dedifferentiation of the exocrine pancreas to a progenitor state (Proc. Nat. Acad Sci. 105, 8962-8967 (2008)) and it remodels the endocrine pancreas (Dev. Biol. 328, 384-391 (2009)). The redifferentiated frog pan...
ORGANISM(S): Xenopus laevis 
2010-05-16 | E-GEOD-16018 | biostudies-arrayexpress
TranscriptomicsAn integrated study to the effects of thermal acclimation in zebrafish
Changes in environmental temperature can profoundly change species habitats and result in populations facing suboptimal environments. Many aquatic organisms are restricted in terms of migration by their habitat requirements. Also due to anthropogenic migration barriers (both physical as well as chem...
ORGANISM(S): Danio rerio 
2010-08-28 | E-GEOD-17756 | biostudies-arrayexpress
TranscriptomicsThyroid Hormone (TH) Controls The Remodeling Of The Pancreas And The Liver, Part A
Thyroid hormone (TH) controls the remodeling of the pancreas and the liver. TH-induces dedifferentiation of the exocrine pancreas to a progenitor state (Proc. Nat. Acad Sci. 105, 8962-8967 (2008)) and it remodels the endocrine pancreas (Dev. Biol. 328, 384-391 (2009)). The redifferentiated frog pan...
ORGANISM(S): Xenopus laevis 
2010-05-16 | E-GEOD-16074 | biostudies-arrayexpress
TranscriptomicsCD3/CD28 Stimulated versus unstimulated Double-negative T Cells From Sooty Mangabeys
Transcriptional profiling of Double Negative (CD4-/CD8-) T-cells isolated from SIV infected Sooty Mangebys. DN T-cells were stimulated through the T-Cell receptor using anti CD3/CD28 antibodies for 4 hours and compared to unstimulated DN T-cells. Two condition experiment, Stimulated vs Unstimulated....
ORGANISM(S): Cercocebus atys 
2012-12-31 | E-GEOD-40781 | biostudies-arrayexpress
TranscriptomicsExpression profiling of human peripheral blood before and after omega 3 dietary supplement.
Patients with early stage CLL were recruited into the study and administered a course of omega 3 dietary supplements. Expression profiling of each patient was performed at baseline (before administering the supplement) and after consumption of supplements. Patients were divided into two groups accor...
ORGANISM(S): Homo sapiens 
2012-12-01 | E-GEOD-29678 | biostudies-arrayexpress
TranscriptomicsThe Influence of Sleep Deprivation on Hippocampal CA1 Gene Expression: Relation to Stress and Aging
Sleep deprivation (SD) in young adults is associated with metabolic, stress and cognitive responses that are also characteristic of brain aging. Given that sleep architecture changes with age, including increased fragmentation and decreased slow wave activity, it seems reasonable to investigate pote...
ORGANISM(S): Rattus norvegicus 
2012-07-16 | E-GEOD-34424 | biostudies-arrayexpress
TranscriptomicsDual leucine zipper kinase is required for excitotoxicity induced neuronal degeneration
To investigate the role of DLK in the adult brain, we generated mice in which excision of the DLK allele can be temporally controlled to avoid the lethality observed at early postnatal ages in DLK null mice (Hirai et al., 2006). This was done by crossing mice with DLK exons 2-5 flanked by loxP sites...
ORGANISM(S): Mus musculus 
2013-08-28 | E-GEOD-50245 | biostudies-arrayexpress
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