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MetabolomicsRegulation of drug resistance to enrofloxacin in Pasteurella multocida strains from cattle by quorum-sensing acyl-homoserine lactone signaling molecules

Pasteurella multocida (Pm) is a significant cause of respiratory disease in beef cattle, with serious consequences for the cattle industry. The bacterial quorum-sensing (QS) system is used for communication and regulation of various processes, including bacterial growth, virulence, biofilm format...

2025-12-18 | MTBLS13502 | MetaboLights
TranscriptomicsRNA-Seq analysis of quorum sensing-dependent genes in Burkholderia glumae BGR1
Burkholderia glumae causes rice grain rot and sheath rot by producing toxoflavin, whose expression is regulated by quorum sensing (QS). The QS systems of the bacterium rely on N-octanoyl homoserine lactone, synthesized by TofI and its cognate receptor TofR, to activate toxoflavin biosynthesis genes ...
ORGANISM(S): Burkholderia glumae 
2012-03-14 | E-GEOD-36485 | biostudies-arrayexpress
TranscriptomicsA transcriptome study of DSF-mediated quorum sensing in Xanthomonas axonopodis pv. citri
Quorum sensing (QS) in Xanthomonas axonopodis pv. citri, the causal agent of citrus canker, is mediated by a diffusible signal factor (DSF). QS is required for the full virulence of X. axonopodis pv. citri in planta. Mutations in rpfF, rpfC and rpfG, the core genes of QS, decreased the production of...
ORGANISM(S): Xanthomonas axonopodis pv. citri str. 306 
2012-04-26 | E-GEOD-29877 | biostudies-arrayexpress
TranscriptomicsLyngbyoic Acid, a "Tagged" Fatty Acid from a Marine Cyanobacterium, Disrupts Quorum Sensing in Pseudomonas aeruginosa
Quorum sensing (QS) is a mechanism of bacterial gene regulation in response to increases in population density. Production of small molecule QS signals, their accumulation within a diffusion-limited environment and their binding to the LuxR-type receptor trigger QS-controlled gene regulatory casca...
ORGANISM(S): Pseudomonas aeruginosa 
2011-01-24 | E-GEOD-22999 | biostudies-arrayexpress
TranscriptomicsExpression profile for PA14 lasR rhlR double mutant with H2O2 stress
Quorum sensing controls the expression of multiple virulence factors. PA14 genes lasR and rhlR are necessary for quorum sensing via homoserine lactones. A PA14 lasR rhlR deficient mutant exhibits a reduced oxidative stress response. Here we conducted a microarray to determine oxidative stress resp...
ORGANISM(S): Pseudomonas aeruginosa 
2015-01-09 | E-GEOD-54245 | biostudies-arrayexpress
ProteomicsStructure and mechanism of CSP secretion pump of ComA for Quorum sensing
Cross-linking MS data for 1) ComA Apo form and 2) ComA +ATP form. Purified proteins were cross-linked with DSSO, digested with either trypsin or chymotrypsin, and acquired by MS2-MS3 acquisition method. 2 technical replicates were acquired for each digested sample.
ORGANISM(S): Cellular Organisms 
2023-08-31 | PXD038058 | JPOST Repository
TranscriptomicsRNA-seq in the broad host range strain Sinorhizobium fredii NGR234 identifies a large set of genes linked to quorum sensing-dependent regulation in the background of a traI and ngrI deletion mutant
The M-NM-1-proteobacterium Sinorhizobium fredii NGR234 has an exceptionally wide host range as it forms nitrogen-fixing nodules with more legumes than any other known microsymbiont. Within its 6.9 Mbp genome it encodes two N-acyl-homoserine-lactone synthase genes (i.e. traI and ngrI) involved in the...
ORGANISM(S): Sinorhizobium fredii NGR234 
2014-07-18 | E-GEOD-54381 | biostudies-arrayexpress
TranscriptomicsTranscriptome-Based Analysis of the Pantoea stewartii Quorum-Sensing Regulon and Identification of EsaR Direct Targets
Introduction: Pantoea stewartii subsp. stewartii is a proteobacterium that causes Stewart’s wilt disease in corn plants. The bacteria form a biofilm in the xylem of infected plants and produce capsule that blocks water transport, eventually causing wilt. At low cell densities, the quorum-sensing (QS...
ORGANISM(S): Pantoea stewartii 
2014-07-22 | E-GEOD-57635 | biostudies-arrayexpress
GenomicsMolecular Mechanisms of Master Regulator VqsM mediating Quorum-sensing and Antibiotic Resistance in Pseudomonas aeruginosa
The Pseudomonas aeruginosa quorum-sensing (QS) systems contribute to bacterial homeostasis and pathogenicity. Although the AraC family transcription factor VqsM has been characterized to control the production of virulence factors and QS signaling molecules, its detailed regulatory mechanisms still ...
ORGANISM(S): Pseudomonas aeruginosa 
2014-08-04 | E-GEOD-57284 | biostudies-arrayexpress
TranscriptomicsThe IclR-family regulator BapR controls biofilms formation in B. cenocepacia H111
In Burkholderia cenocepacia H111, the large surface protein BapA plays a crucial role in the formation of highly structured communities, known as biofilms. We have recently demonstrated that Quorum sensing (QS) is necessary for the maximal expression of bapA. In this study we identify a protein from...
ORGANISM(S): Burkholderia cenocepacia H111 
2014-03-26 | E-GEOD-52769 | biostudies-arrayexpress
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