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Proteomics4 RABs proxymity labelling - APEX2-mediated RAB proximity labeling identifies a role for RAB21 in clathrin-independent cargo sorting
APEX2-mediated proximity labeling was performed with 4 endosomal RABs allowed an efficient and comprehensive identification of their protein neighbors. APEX2-mediated proximity labeling was performed in triplicate. Protein enrichments obtained from all RABs were compared to APEX2-nude proximity labe...
ORGANISM(S): Homo sapiens (Human) 
2019-01-07 | PXD010950 | Pride
Early endosomes Apex2 Rabs Membrane trafficking 
ProteomicsChlamydophila psittaci negative ocular adnexal marginal zone lymphomas express self polyreactive B cell receptors
The pathogenesis of Chlamydophila (C.) psittaci negative ocular adnexal extranodal marginal zone lymphomas (OAEMZLs) is poorly understood. OAEMZLs are monoclonal tumors expressing a biased repertoire of mutated surface immunoglobulins. Antigenic activation of the B cell receptor (BCR) may play a rol...
ORGANISM(S): Homo sapiens 
2015-01-30 | E-GEOD-65443 | biostudies-arrayexpress
UnknownRabs and their effectors: achieving specificity in membrane traffic.
Not available
S-EPMC1567661 | biostudies-literature
UnknownPlant RABs: Role in Development and in Abiotic and Biotic Stress Responses.
Not available
S-EPMC8142350 | biostudies-literature
UnknownEpistatic Analysis of the Contribution of Rabs and Kifs to CATCHR Family Dependent Golgi Organization.
Not available
S-EPMC6687757 | biostudies-literature
TranscriptomicsTranscription profiling of peripheral blood or primary finroblast cultures from choroideremia patients to determine if loss-of-function mutations in REP-1 affect intracellular vesicle transport in fibroblasts and monocytes of CHM patients
Choroideremia (CHM) is a progressive X-linked retinopathy caused by mutations in the CHM gene, which encodes Rab escort protein-1 (REP-1), an escort protein involved in the prenylation of Rabs. Under-prenylation of certain Rabs, as a result of loss of function mutations in REP-1, could affect vesicu...
ORGANISM(S): Homo sapiens 
2010-02-21 | E-GEOD-17549 | biostudies-arrayexpress
UnknownComprehensive Analysis of Expression, Clinicopathological Association and Potential Prognostic Significance of RABs in Pancreatic Cancer.
Not available
S-EPMC7432855 | biostudies-literature
UnknownEMT activates exocytotic Rabs to coordinate invasion and immunosuppression in lung cancer.
Not available
S-EPMC10334751 | biostudies-literature
UnknownEndocytic Rabs Are Recruited to the Trypanosoma cruzi Parasitophorous Vacuole and Contribute to the Process of Infection in Non-professional Phagocytic Cells.
Not available
S-EPMC7658340 | biostudies-literature
ProteomicsRAB GTPase proximity interactome
RAB GTPases represent the most abundant family of small GTPases and regulate multiple aspects of membrane trafficking events, from cargo sorting to vesicle budding, transport, docking, and fusion. To control these processes, RABs are tightly regulated by guanine exchange factors (GEFs) and GTPase-ac...
ORGANISM(S): Homo sapiens (Human) 
2025-12-02 | PXD057404 | Pride
Rab gtpase Apex2 Membrane trafficking Bioid 
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