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GenomicNHLBI TOPMed: The Genetic Epidemiology of Asthma in Costa Rica

This administrative supplement to the project, "The Genetic Epidemiology of Asthma in Costa Rica" (R37 HL066289) is in response to NOT-HL-14-029 to perform whole genome sequencing (WGS) on existing NHLBI populations. We focus on asthma because of its public health significance. Asthma affe...

phs000988 | dbGaP
TranscriptomicsMapping of disease-associated expression polymorphisms in primary peripheral blood CD4+ lymphocytes
Analysis of expression quantitative trait loci (eQTLs) using RNA derived from freshly harvested peripheral blood CD4+ lymphocytes from 200 asthmatics collected in clinical settings. RNA was obtained from peripheral blood CD4+ lymphocytes at four study centers. Peripheral blood (17 cc) was collected ...
ORGANISM(S): Homo sapiens 
2010-06-23 | E-GEOD-22324 | biostudies-arrayexpress
GenomicsGenome Wide Association for Asthma and Lung Function

The SNP Typing for Association with Multiple Phenotypes from Existing Epidemiologic (STAMPEED) asthma project includes subjects with asthma and controls from the Chicago Asthma Genetics Study (CAG), NHLBI multicenter Severe Asthma Research Program (SARP) and NHLBI Collaborative Studies ...

phs000355.v1.p1 | EGA
TranscriptomicsGlobal analysis of the impact of environmental perturbation on cis-regulation of gene expression: control and variety of treatments, 2hr and 24hr
Genetic variants altering cis-regulation of normal gene expression (cis-eQTLs) have been extensively mapped in human cells and tissues, but the extent to which environmental perturbation influences such traits has not been studied to date. We carried out large-scale induction experiments using prima...
ORGANISM(S): Homo sapiens 
2010-10-01 | E-GEOD-21727 | biostudies-arrayexpress
TranscriptomicsGlobal analysis of the impact of environmental perturbation on cis-regulation of gene expression: BMP2, 2hr
Genetic variants altering cis-regulation of normal gene expression (cis-eQTLs) have been extensively mapped in human cells and tissues, but the extent to which environmental perturbation influences such traits has not been studied to date. We carried out large-scale induction experiments using prima...
ORGANISM(S): Homo sapiens 
2010-10-01 | E-GEOD-21410 | biostudies-arrayexpress
TranscriptomicsGlobal analysis of the impact of environmental perturbation on cis-regulation of gene expression: DEX, 24hr
Genetic variants altering cis-regulation of normal gene expression (cis-eQTLs) have been extensively mapped in human cells and tissues, but the extent to which environmental perturbation influences such traits has not been studied to date. We carried out large-scale induction experiments using prima...
ORGANISM(S): Homo sapiens 
2010-10-01 | E-GEOD-21725 | biostudies-arrayexpress
TranscriptomicsGlobal analysis of the impact of environmental perturbation on cis-regulation of gene expression: PGE2, 24hr
Genetic variants altering cis-regulation of normal gene expression (cis-eQTLs) have been extensively mapped in human cells and tissues, but the extent to which environmental perturbation influences such traits has not been studied to date. We carried out large-scale induction experiments using prima...
ORGANISM(S): Homo sapiens 
2010-10-01 | E-GEOD-21726 | biostudies-arrayexpress
UnknownWhole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children With Asthma.
Not available
S-EPMC6904857 | biostudies-literature
UnknownSARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.
Not available
S-EPMC7995808 | biostudies-literature
UnknownA prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.
Not available
S-EPMC12056793 | biostudies-literature
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