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ProteomicsProtease activity profiling of ovarian clear cell carcinoma
Ovarian clear cell carcinoma (OCCC) is an understudied poor prognosis subtype of ovarian cancer lacking in effective molecularly targeted therapies; efforts to define drivers of OCCC malignancy may lead to new therapeutic targets and approaches. Among potential targets are secreted proteases, enzyme...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-05-07 | MSV000087385 | MassIVE
TranscriptomicsMMP3 treatment of Panc-2 cells
Response of pancreas cancer cells to treatment with recombinant MMP3 Cells were treated with 100U/ml MMP3 for 4 days, then isolated for RNA. The submitted experiments represent two different experiments performed at different times
ORGANISM(S): Homo sapiens 
2014-05-29 | E-GEOD-50931 | biostudies-arrayexpress
UnknownMMP3 treatment of Panc-2 cells
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-50931 | biostudies-other
TranscriptomicsExpression data from MMP3 and control transgenic mice
Effect of induction of MMP3 expression in CCSP-rtTA/tet-MMP3 transgenic mice, fed doxycycline for 14 weeks We used microarrays to detail the global programme of gene expression following MMP3 expression Transgenic mice (CCSPrt-TA/tet-MMP3 or CCSPrtTA control mice) were fed doxycycline from week 6 to...
ORGANISM(S): Mus musculus 
2010-11-18 | E-GEOD-25439 | biostudies-arrayexpress
TranscriptomicsMMP3 treatment of SCp2 mouse mammary epithelial cells
Response of mouse mammary epithelial cells to treatment with MMP3 Cells were untreated (d1 control) or treated with MMP3 for 1-4 days (d1-4 MMP3), or washed and then allowed to recover for three additional days (d5-7 recover) then isolated for RNA.
ORGANISM(S): Mus musculus 
2014-09-30 | E-GEOD-56909 | biostudies-arrayexpress
TranscriptomicsAn Integrated Model of the Transcriptome Landscape of HER2-Positive Breast Cancer
The goal of our study is to build an integrated transcriptome landscape model for HER2 positive breast tumors and identify the crucial signaling pathways associated with HER2 tumors. Genomic features include, 685 genes that were differentially expressed only in HER2-positive tumors, 102 genes that w...
ORGANISM(S): Homo sapiens 
2013-12-06 | E-GEOD-45419 | biostudies-arrayexpress
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