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UnknownNetwork signatures link hepatic effects of anti-diabetic interventions with systemic disease parameters.
Not available
S-EPMC4363943 | biostudies-literature
TranscriptomicsTranscription profiling by array of mouse peripheral blood mononuclear cells from ApoE3*Leiden mice on a high-fat diet
The aim of experiment was to investigate gene expression changes over time in liver of ApoE3*Leiden mice on a high-fat diet. Transformed file with remapped and annotated probesets into Entrez gene-ids using the custom MBNI CDF-file (http://brainarray.mbni.med.umich.edu/Brainarray/Database/CustomCDF/...
ORGANISM(S): Mus musculus 
2011-04-01 | E-TABM-959 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of the temporal hepatic response to high-fat diets in ApoE3 Leiden mice
A time-course study of the effects of two types of high-fat diets on liver transcriptome in the context of metabolic syndrome development using ApoE3Leiden mice
ORGANISM(S): Mus musculus 
2009-08-01 | E-TABM-553 | biostudies-arrayexpress
TranscriptomicsSystems biology analysis unravels complementary action of combined Rosuvastatin and Ezetimibe therapy
Transcriptomics analysis to understand both efficacy and side effects of a cholesterol lowering drug combination therapy based on biological pathways and molecular processes affected by each drug alone or in combination. We have treated ApoE*3Leiden mice, a humanized atherosclerosis model with a uni...
ORGANISM(S): Mus musculus 
2013-02-27 | E-GEOD-38688 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human HUVEC (Human Umbilical Vein Endothelial Cells) cells exposed to heat shock (42 degrees Celcius) for different time points (1hr, 3 hrs, 6 hr and 12 hrs) and vs non heat-shock cells with varying amounts of external spikes added
HUVEC (Human Umbilical Vein Endothelial Cells) cells were exposed to heat shock (42 degrees Celcius) for different time points (1hr, 3 hrs, 6 hr and 12 hrs) and compared to non heat-shock cells. External normalization controls were added in equal amounts to equivalent amounts of total RNA.
ORGANISM(S): Homo sapiens 
2003-04-01 | E-UMCU-2 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of wild type vs wild type yeast with controls spiked in different ratios; 1:1, 1:2 and 1:10 respectively
Wild type versus wildtype Saccharomyces cerevisiae experiment with controls spiked in different ratios; 1:1, 1:2 and 1:10 respectively
ORGANISM(S): Saccharomyces cerevisiae 
2003-04-01 | E-UMCU-1 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of MCF7 (human mammary gland adenocarcinoma) cells deprived of serum for 30 hrs and vs non-deprived cells to test spike based normalization
MCF7 (human mammary gland adenocarcinoma) cells were deprived of serum for 30 hrs and were compared to non-deprived cells. External normalization controls were added in equal amounts to equivalent amounts of total RNA.
ORGANISM(S): Homo sapiens 
2003-04-01 | E-UMCU-3 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of yeast cells grown into stationary phase compared with exponential mid-log grown cells including a dye-swap
S. cerevisiae cells grown into stationary phase were compared with exponential mid-log grown cells including a dye-swap. External normalization controls were added in equal amounts to equivalent amounts of total RNA.
ORGANISM(S): Saccharomyces cerevisiae 
2003-04-01 | E-UMCU-4 | biostudies-arrayexpress
TranscriptomicsA systems biology approach to understand the pathophysiological mechanisms of cardiac pathological hypertrophy associated with rosiglitazone
Cardiac pathological hypertrophy is associated with a significantly increased risk of coronary heart disease and has been observed in diabetic patients treated with rosiglitazone, whereas most published studies do not suggest a similar increase in risk of cardiovascular events in pioglitazone-treate...
ORGANISM(S): Mus musculus 
2014-06-30 | E-GEOD-48977 | biostudies-arrayexpress
TranscriptomicsPairwise comparison stationary phase vs mid-log
A pairwise comparison was performed between stationary phase specific samples and mid-log samples using four replicates and dye-swaps
ORGANISM(S): Saccharomyces cerevisiae 
2005-04-15 | E-UMCU-13 | biostudies-arrayexpress
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