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TranscriptomicsTranscription profiling by array of Saccharomyces cerevisiae BY4741 wt and YDL090C Delta ram1 cells.
The goal of these experiments was to determine the global expression profile response of budding yeast to a genetic block of Farnesyl Transferase (FTase). We blocked this enzyme using cells that harbour a deletion of the RAM1 gene, which encodes one of the two subunits of FTase. We compared the cell...
ORGANISM(S): Saccharomyces cerevisiae 
2011-03-30 | E-MTAB-216 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array Saccharomyces cerevisiae after GGTI-298 treatment.
Global gene expression on yeast cells was determined after a drug induced inhibition of GGTase I by treating yeast cells with GGTI298 (Cabiochem). GGTI298 treated cells were grown for 2 generations to exponential phase in parallel with untreated cells. RNA was extracted, subsequently cDNAs were labe...
ORGANISM(S): Saccharomyces cerevisiae 
2011-03-30 | E-MTAB-217 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of Saccharomyces cerevisiae wild type cells after FTase Inhibitor treatment.
Global gene expression on yeast cells was determined after a drug induced inhibition of FTase by treating yeast cells with FTase Inhibitor I (FTI, Cabiochem). FTI treated cells were grown for 2 generations to exponential phase in parallel with untreated cells. RNA was extracted, subsequently cDNAs w...
ORGANISM(S): Saccharomyces cerevisiae 
2011-03-21 | E-MTAB-215 | biostudies-arrayexpress
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