Rai Alin A - OmicsDI

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Heart surfaceome profiling using biotin capture

Cell surface proteins (surfaceome) represent key signalling and interaction molecules for therapeutic targeting, biomarker profiling, and cellular phenotyping. Understanding the surfaceome of complex tissues including the heart is essential to investigate membrane composition and function in physiol...

ORGANISM(S): Mus Musculus (ncbitaxon:10090)

MSV000095912 | MassIVE

Rapid and in-depth proteomic profiling of small extracellular vesicles for ultralow samples

The form and function of extracellular vesicles (EV) is defined by their proteome. This knowledge is essential to describe and understand EVs, encompassing their marker proteins, capacity as a signalling platform, and utility as diagnostic tools and therapeutic targets. However, EV are low-abundant ...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2023-08-16 | MSV000092668 | MassIVE

intercardiac Phosphoproteome/proteome regulation of cardiomyocyte-fibroblast signaling

Secretome-mediated signaling from human iPSC-derived cardiomyocytes (TGF-beta induced dysfunction) to primary human cardiac fibroblasts was investigated to identify downstream regulators of fibrosis. Quantitative proteomic profiling revealed a dynamic reprogramming of fibroblast global proteome, wit...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2023-06-27 | MSV000092293 | MassIVE

Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.

Not available

S-EPMC10831058 | biostudies-literature

Empagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.

Not available

S-EPMC10957483 | biostudies-literature

Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis.

Not available

S-EPMC9333998 | biostudies-literature

Higher dose corticosteroids in hospitalised COVID-19 patients requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial.