Ralser Markus M

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Proteomics (45)
Metabolomics (2)
Models (1)

Organisms

Schizosaccharomyces pombe (41)
Human immunodeficiency virus 1 (41)
Oryza sativa Indica Group (41)
Sinorhizobium meliloti BL225C (41)
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Repository

pride (41)
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Technology Type

Mass Spectrometry (41)
SWATH MS (28)
Data-independent acquisition (12)
Bottom-up proteomics (6)
Mass spectrometry (2)
SRM/MRM (2)
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DiaPASEF (1)
HDMSE (1)

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TripleTOF 6600 (2)
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CHEBI ID

CHEBI:16027 (1)
CHEBI:28602 (1)
CHEBI:48153 (1)
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CHEBI:16474 (1)
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CHEBI:18021 (1)
CHEBI:15946 (1)

Metabolite Name

Tryptophan (2)
Serine (2)
Proline (2)
Lysine (2)
Glutamate (2)
Aspartate (2)
Asparagine (2)
Arginine (2)
Histidine (2)
Phenylalanine (2)
Tyrosine (2)
Methionine (2)
Glutamine (2)
Alanine (2)
Valine (2)
Isoleucine (2)
Leucine (2)
Glycine (2)
Xylose (1)
Xanthurenate (1)
Valerylglycine (1)
Ursodeoxycholate (1)
Undecanedioate (1)
Trimethylamine N-oxide (1)
Trigonelline (N'-methylnicotinate) (1)
Tricarballylate (1)
Trans-urocanate (1)
Trans-4-hydroxyproline (1)
Tiglylcarnitine (1)
Tigloylglycine (1)

IsPrivate

False (1)

Modelling Approach

Ordinary differential equation model (1)

Lab affiliation

Charité Universitätsmedizin, Department of Biochemistry, 10117 Berlin, Germany The Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK Max Planck Institute for Molecular Genetics, Berlin, Germany (4)
Markus Ralser, Prof. Dr. Einstein Professor of Biochemistry Head, Institute of Biochemistry, Charité University Medicine, Berlin markus.ralser@charite.de Senior Group Leader, The Francis Crick Institute, London markus.ralser@crick.ac.uk (3)
Department of Biochemistry, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany (2)
Charité – Universitätsmedizin Berlin, Department of Biochemistry, 10117 Berlin, Germany; The Francis Crick Institute, Molecular Biology of Metabolism Laboratory, London NW11AT, UK (2)
Charité Universitätsmedizin Berlin, Institute of Biochemistry (2)
Charité - Universitätsmedizin Berlin Research group Biochemistry and Systems Biology of the Metabolism Institute of Biochemistry Germany (2)
The Francis Crick Institute, Molecular Biology of Metabolism laboratory, London, United Kingdom; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, United Kingdom; Department of Biochemistry, Charité Universitaetsmedizin Berlin, Berlin, Germany (1)
Volker Boehm Gehring Lab, Institute for Genetics, University of Cologne, 50674 Cologne, Germany (1)
Charité Universitätsmedizin Berlin, Department of Biochemistry, 10117 Berlin, Germany The Francis Crick Institute, Molecular Biology of Metabolism Laboratory, London NW1 1AT, UK The Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, UK Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany (1)
Einstein Professor of Biochemistry Head, Institute of Biochemistry, Charité Universitätsmedizin Berlin, Germany markus.ralser@charite.de Senior Group Leader, The Francis Crick Institute, London, UK markus.ralser@crick.ac.uk (1)
1)Department of Biochemistry, Charité – Universitätsmedizin Berlin, Berlin, Germany. 2)The Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, UK 3)Max Planck Institute for Molecular Genetics, Berlin, Germany (1)
Charité Universitätsmedizin – Chariteplatz 1, 10117 Berlin (1)
Charité Universitätsmedizin Berlin, Germany (1)
Einstein Professor of Biochemistry Head, Institute of Biochemistry, Charité University Medicine, Berlin markus.ralser@charite.de Senior Group Leader, The Francis Crick Institute, London markus.ralser@crick.ac.uk UK 0044 743 5315249 DE 0049 30 450528141 (1)
Cambridge Centre for Proteomics, Department of Biochemistry, University of Cambridge, Cambridge, U.K. (1)
Department of Biochemistry, Charité University Medicine, Berlin, Germany (1)
Charité – Universitätsmedizin Berlin, Department of Biochemistry, 10117 Berlin, Germany (1)
Charite – Universitaetsmedizin Berlin (1)
Department of Biochemistry, Charite Universitaetsmedizin Berlin, Germany (1)
Department of Biochemistry, Charité Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany Berlin Institute of Health (BIH) at Charité Universitätsmedizin Berlin, Berlin, Germany The Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Roosevelt Dr, Headington, Oxford OX3 7BN, UK (1)
Einstein Professor of Biochemistry Head, Institute of Biochemistry, Charité University Medicine, Berlin (1)
The Francis Crick Institute; Charité – Universitätsmedizin Berlin (1)
Charité Universitätsmedizin Berlin, Department of Biochemistry, Berlin, Germany (1)
Department of Biochemistry, Charité Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany Berlin Institute of Health (BIH) at Charité Universitätsmedizin Berlin, Berlin, Germany The Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Roosevelt Dr, Headington, Oxford OX3 7BN, UK (1)
Charité Universitaetsmedizin (1)
Department of Biochemistry, Charité Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany Berlin Institute of Health (BIH) at Charité Universitätsmedizin Berlin, Berlin, Germany The Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Roosevelt Dr, Headington, Oxford OX3 7BN, UK (1)
Charite universitymedicine berlin (1)
The Francis Crick Institute, UK Charité – Universitätsmedizin Berlin, Germany (1)
Markus Ralser, Prof. Dr. Einstein Professor of Biochemistry Head, Institute of Biochemistry, Charité University Medicine, Berlin markus.ralser@charite.de Senior Group Leader, The Francis Crick Institute, London markus.ralser@crick.ac.uk UK 0044 743 5315249 DE 0049 30 450528141 (1)
Charité Universitätsmedizin Berlin (1)

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Ralser2007_Carbohydrate_Rerouting_ROS

This is the model with unfitted parameters described in the article Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress Markus Ralser, Mirjam M Wamelink, Axel Kowald, Birgit Gerisch, Gino Heeren, Eduard A Struys, Edda Kl...

2024-09-02 | BIOMD0000000247 | BioModels

Proteomes of gastrointestinal tract organoids

Examination of differential susceptibility of the gastric, small intestine and colon epithelium to SARS-CoV-2 infection Data used in the manuscript "SARS-CoV-2 tropism to intestinal but not gastric epithelial cells is defined by limited ACE2 expression" (Pauzuolis M, Fatykhova D, Zühlke B, Schwecke ...

ORGANISM(S): Homo sapiens (Human)

2024-03-20 | PXD044789 | Pride

ALSPAC human inflammation plasma proteomics

The project aimed at investigating the impact of chronic low grade inflammation on plasma functions and plasma proteomes in healthy individuals.

ORGANISM(S): Homo sapiens (Human)

2022-11-26 | PXD037682 | Pride

Proteomics Avon longitudinal study of parents and children – alspac Inflammation Human Plasma

Plasma proteomics in mouse sepsis

Analysis of plasma proteomes from 8 week old C57BL/6J WT or TCRα-/- (Tcratm1Phi) either naïve or infected by intravenous injection of 5x105 yeast (clinical isolate SC5314), and collected 72 hrs post-infection

ORGANISM(S): Mus musculus (Mouse)

2022-11-26 | PXD037676 | Pride

Mice plasma proteomics sepsis

Human sepsis with plasma samples

The project examines the mechanisms of neutrophil dysfunction during sepsis. Our work uncovered the central role of cell free circulating histones in eliminating mature neutrophil in favour of immature cells and characterized the mechanisms that regulate their release following systemic infection. M...

ORGANISM(S): Homo sapiens (Human)

2022-07-01 | PXD034391 | Pride

Human plasma sepsis

Fast proteomics with dia-PASEF and analytical flow-rate chromatography

The presented approach is a combination of analytical flow rate chromatography with ion mobility separation of peptide ions, data-independent acquisition, and raw data processing using the DIA-NN software suite, to conduct fast, low-cost proteomic experiments that only require moderate sample amount...

ORGANISM(S): Escherichia Coli (ncbitaxon:562) Homo Sapiens (ncbitaxon:9606)

2024-10-24 | MSV000096202 | MassIVE

Human plasma proteome of caloric restriction

We recruited ten normal-weight healthy men using inclusion criteria as previously described (Collet et al 2017). All males were healthy and not obese or overweight (average age: 23.8 years, average BMI (kg/m2): 23.3). Participants at baseline consumed a balanced diet (50% carbohydrate, 30% fat, and ...

ORGANISM(S): Homo sapiens (Human)

2022-12-12 | PXD038526 | Pride

Refeeding Proteomics Human Caloric restriction Plasma Proteome

Cross-platform clinical proteomics using the Charité open standard for plasma proteomics (OSPP)

Based on large serum and plasma proteome studies, we generate the Charité Open Peptide Standard for Plasma Proteomics (OSPP), an open, versatile peptide internal standard for targeted and untargeted mass spectrometry-based proteomic studies. The OSPP includes 211 concentration-matched stable-isotope...

ORGANISM(S): Homo Sapiens

PXD083958 |

Functional Metabolomics Describes the Yeast Biosynthetic Regulome

Genome-metabolism interactions enable cell growth. To probe the extent of these interactions and delineate their functional contributions, we quantified the Saccharomyces amino acid metabolome and its response to systematic gene deletion. Over one-third of coding genes, in particular those important...

2017-03-02 | MTBLS434 | MetaboLights

The metabolic background is a global player in Saccharomyces gene expression epistasis

The regulation of gene expression in response to nutrient availability is fundamental to the genotype-phenotype relationship. The metabolic-genetic make-up of the cell, as reflected in auxotrophy, is hence likely to be a determinant of gene expression. Here, we address the importance of the metaboli...

2016-12-16 | MTBLS168 | MetaboLights

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48 Results

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