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TranscriptomicsHigh-Throughput Single-Cell Labeling (Hi-SCL) for RNA-Seq using drop-based microfluidics
The importance of single-cell level data is increasingly appreciated, and significant advances in this direction have been made in recent years. Common to these technologies is the need to physically segregate individual cells into containers, such as wells or chambers of a micro-fluidics chip. High...
ORGANISM(S): Mus musculus 
2015-06-05 | E-GEOD-62050 | biostudies-arrayexpress
GenomicsCombinatorial patterning of chromatin regulators uncovered by genome-wide location analysis in human cells
Hundreds of Chromatin Regulators (CRs) control chromatin structure and function by catalyzing and binding histone modifications, yet the rules governing these key processes remain obscure. Here, we present a systematic approach to infer CR function. We developed ChIP-string, a meso-scale assay that ...
ORGANISM(S): Homo sapiens 
2011-12-23 | E-GEOD-32509 | biostudies-arrayexpress
UnknownAntisense oligonucleotide-based drug development for Cystic Fibrosis patients carrying the 3849+10 kb C-to-T splicing mutation.
Not available
S-EPMC8464507 | biostudies-literature
TranscriptomicsAn Integrated Approach to Uncover Drivers of Cancer
We developed a computational framework that integrates chromosomal copy number and gene expression data for detecting aberrations that promote cancer progression. We demonstrate the utility of this framework using a melanoma dataset. Our analysis correctly identified known drivers of melanoma and pr...
ORGANISM(S): Homo sapiens 
2010-12-01 | E-GEOD-23884 | biostudies-arrayexpress
UnknownGlobal, regional, and national burden of tuberculosis, 1990-2016: results from the Global Burden of Diseases, Injuries, and Risk Factors 2016 Study.
Not available
S-EPMC6250050 | biostudies-literature
UnknownSpatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990-2019: a systematic analysis from the Global Burden of Disease Study 2019.
Not available
S-EPMC8223261 | biostudies-literature
UnknownGlobal, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.
Not available
S-EPMC5614451 | biostudies-literature
UnknownAlcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.
Not available
S-EPMC6148333 | biostudies-literature
UnknownGlobal, regional, and national burden of neurological disorders, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.
Not available
S-EPMC6459001 | biostudies-literature
UnknownAge-sex differences in the global burden of lower respiratory infections and risk factors, 1990-2019: results from the Global Burden of Disease Study 2019.
Not available
S-EPMC9605880 | biostudies-literature
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