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ProteomicsComparing the proteome of human induced pluripotent stem cells cultured during normoxic versus hypoxic conditions
Human induced pluripotent stem cells (hiPSCs) have become an invaluable tool to study molecular disease mechanisms on a human genetic background as they can be differentiated in different cell types including cardiac myocytes. One major downside that has decelerated the research performed in hiPSCs ...
ORGANISM(S): Homo sapiens (Human) 
2025-01-07 | PXD050410 | Pride
Normoxia Proteome remodeling Hypoxia Stem cells 
ProteomicsComplexome profiling of human induced pluripotent stem cells cultured during normoxic versus hypoxic conditions
Human induced pluripotent stem cells (hiPSCs) have become an invaluable tool for studying molecular disease mechanisms on a human genetic background. They can be differentiated into different cell types, including cardiac myocytes. Here, we studied the remodeling of mitochondrial protein complexes o...
ORGANISM(S): Homo sapiens (Human) 
2025-01-07 | PXD048535 | Pride
Normoxia Complexome remodeling Hypoxia Stem cells 
TranscriptomicsTranslocations Activating IRF4 Identify a Subtype of Germinal-Center-Derived B-cell Lymphoma Affecting Predominantly Children and Young Adults
Background: Germinal center B-cell (GCB) lymphomas are common in children and adults. The prognosis strongly depends on age. Subgroups of GCB-lymphomas are characterized by chromosomal translocations affecting immunoglobulin (IG) loci leading to oncogene deregulation. Methods: Novel IG translocation...
ORGANISM(S): Homo sapiens 
2011-06-24 | E-GEOD-22470 | biostudies-arrayexpress
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