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MetabolomicsYeast glycolysis in normoxia and hypoxia (150107_pfk2)
Not available
ORGANISM(S): Saccharomyces cerevisiae 
ST000156 | MetabolomicsWorkbench
GenomicsGenome-wide mapping of HIF-2α binding under normoxia in human bronchial epithelial cells (BEAS-2B)
Growing number of cancer (stem) cells and stem cells were described to accommodate constituent active HIF-2α under normoxia. Previous study of hypoxia effect may have obscured some of normoxic HIF-2α functions as hypoxia inducible features. Our interest in study of protective potential of HIFs in ...
ORGANISM(S): Homo sapiens 
2016-07-06 | E-GEOD-81635 | biostudies-arrayexpress
ProteomicsRegulation of mitochondrial function and protein homeostasis by hypoxia inducible factor 1 alpha in normoxia-mouse tissues
Hypoxia inducible factors (HIF), specifically, HIF1A, is continuously synthesized and degraded rapidly in normoxia. During hypoxia, HIF1A stabilization limits oxygen utilization and inhibits protein synthesis, but there are limited data on HIF1A function(s) in normoxia. Given the high energy needs o...
ORGANISM(S): Mus musculus (Mouse) 
2025-06-09 | PXD041880 | Pride
Normoxia Hif1a Skeletal muscle Senescence 
ProteomicsRegulation of mitochondrial function and protein homeostasis by hypoxia inducible factor 1 alpha in normoxia-mouse cells
Hypoxia inducible factors (HIF), specifically, HIF1A, is continuously synthesized and degraded rapidly in normoxia. During hypoxia, HIF1A stabilization limits oxygen utilization and inhibits protein synthesis, but there are limited data on HIF1A function(s) in normoxia. Given the high energy needs o...
ORGANISM(S): Mus musculus (Mouse) 
2025-06-09 | PXD045794 | Pride
Normoxia Hif1a Skeletal muscle Senescence 
ProteomicsMitochondria EglN1 drivers breast cancer progression by controlling metabolic adatation to hypoxic stress
Hypoxia is a hallmark of solid tumors. Mitochondria play essential roles in cellular adaptation to hypoxia, but the underlying mechanisms are not fully understood. Through mitochondrial proteomic profiling, we find that the prolyl hydroxylase EglN1 accumulates on mitochondria under hypoxia. EglN1 su...
ORGANISM(S): Homo sapiens (Human) 
2023-08-29 | PXD041653 | Pride
T47d normoxia and hyppoxia mitochondria ms 
GenomicsNormoxia and Hypoxia transcriptomics
Normoxia and Hypoxia transcriptomics
PRJNA1177809 | ENA
TranscriptomicsTranscription profiling of Lymphatic endothelial cells were grown under normoxia, hypoxia (1% 0xygen) and conditioned media from NSLCN growth under normoxia or hypoxia
Lymphatic endothelial cells were grown under normoxia, hypoxia (1% 0xygen) and conditioned medio from NSLCN growth under normoxia or hypoxia. Gene expression was measured and comparition between samples performed Experiment Overall Design: RNA from different donnors where extracted, pooled to avoid ...
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-5579 | biostudies-arrayexpress
TranscriptomicsJMJD2B knockdown treatment in normoxia and hypoxia
Estrogen receptor alpha plays a critical role in breast cancer and is a major target in endocrine therapy. HIF-1 alpha have been associated with ER alpha and predict a worse outcome. Recent studies indicate that histone demethylase JMJD2B is a HIF-1 alpha target. However, little is known about the b...
ORGANISM(S): Homo sapiens 
2010-09-01 | E-GEOD-18384 | biostudies-arrayexpress
GenomicsEffect of hypoxia and normoxia in Pancreatic Ductal Adenocarcinoma
Effect of hypoxia and normoxia in Pancreatic Ductal Adenocarcinoma
PRJNA922186 | ENA
TranscriptomicsTranscriptomics Responses to Hypoxia and Ketamine in Ovine Fetal Cerebral Cortex
Transient hypoxia in pregnancy stimulates a physiological reflex response that redistributes blood flow and defends oxygen delivery to the fetal brain. The chemoreceptor reflex that is responsible for this physiological response is dependent on glutamatergic neurotransmission which, in times of vig...
ORGANISM(S): Ovis aries 
2016-04-06 | E-GEOD-76110 | biostudies-arrayexpress
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