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UnknownFirst report of Dicopuslongipes (Subba Rao) (Hymenoptera: Chalcidoidea) from India with new distribution data on some species.
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S-EPMC4355647 | biostudies-literature
ProteomicsOGT controls mammalian cell viability by regulating the proteasome/mTOR/mitochondrial axis
TMT-based proteomic and phosphoproteomic analysis of mouse embryonic stem cells upon deletion of Ogt.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2021-11-16 | MSV000088393 | MassIVE
Transcriptomicsnaive/activated ANOVA group
In order to identify genes with differential gene expression or alternative splicing between the groups naive and activated we study 4 hybridizations on the Human Exon 1.0 ST array using mixed model analysis of variance. 1904 genes with significant gene expression differences between the groups and...
ORGANISM(S): Homo sapiens 
2010-09-21 | E-GEOD-11832 | biostudies-arrayexpress
TranscriptomicsLL-sh4/uninfected/shGFP ANOVA group
In order to identify genes with differential gene expression or alternative splicing between the groups LL-sh4, uninfected, and shGFP we study 6 hybridizations on the Human Exon 1.0 ST array using mixed model analysis of variance. 842 genes with significant gene expression differences between the g...
ORGANISM(S): Homo sapiens 
2010-09-15 | E-GEOD-11833 | biostudies-arrayexpress
TranscriptomicsA microRNA-directed program of cytotoxic CD8+ T cell differentiation
Acquisition of effector properties is a key step in the generation of cytotoxic T lymphocytes (CTLs). Here we show that inflammatory signals regulate Dicer expression in CTL, and that deletion or depletion of Dicer in mouse or human activated CD8+ T cells causes upregulation of perforin, granzyme an...
ORGANISM(S): Mus musculus 
2013-12-02 | E-GEOD-51393 | biostudies-arrayexpress
TranscriptomicsDissecting the dynamic changes of 5-hydroxymethylcytosine in T cell development and differentiation [RNA-Seq]
The discovery of TET proteins, enzymes that oxidize 5-methylcytosine (5mC) in DNA, has revealed novel mechanisms for the regulation of DNA methylation. We have mapped 5-hydroxymethylcytosine (5hmC) at different stages of T cell development in the thymus and T cell differentiation in the periphery. ...
ORGANISM(S): Mus musculus 
2014-08-04 | E-GEOD-59121 | biostudies-arrayexpress
TranscriptomicsDistinct roles of Tet1 and Tet2 in mouse embryonic stem cells (RNA-Seq)
The TET proteins TET1, TET2 and TET3 constitute a new family of dioxygenases that utilize molecular oxygen and the cofactors Fe(II) and 2-oxoglutarate to convert 5-methylcytosine (5mC) to 5-hydroxy-methylcytosine (5hmC) and further oxidation products in DNA1-5. Here we show that Tet1 and Tet2 have d...
ORGANISM(S): Mus musculus 
2014-01-16 | E-GEOD-50198 | biostudies-arrayexpress
GenomicsDissecting the dynamic changes of 5-hydroxymethylcytosine in T cell development and differentiation [ChIP-Seq]
The discovery of TET proteins, enzymes that oxidize 5-methylcytosine (5mC) in DNA, has revealed novel mechanisms for the regulation of DNA methylation. We have mapped 5-hydroxymethylcytosine (5hmC) at different stages of T cell development in the thymus and T cell differentiation in the periphery. ...
ORGANISM(S): Mus musculus 
2014-08-04 | E-GEOD-59117 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of control and ELL2-depleted MPC11 plasmacytoma cell lines
We report RNA-Seq data from MPC11 plasmacytoma cell lines transduced with either control hairpins (shGFP) or hairpins targeting the transcriptional elongation factor ELL2. ELL2 has been identified as regulating the alternative splicing and polyadenylation of immunoglobulin pre-mRNA, and is highly e...
ORGANISM(S): Mus musculus 
2012-09-07 | E-GEOD-40285 | biostudies-arrayexpress
TranscriptomicsGenome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells
5hmC and TET proteins have been implicated in stem cell biology and cancer, but information on the genome-wide distribution of 5hmC is limited. Here we describe two novel and specific approaches to profile the genomic localisation of 5hmC. The first approach, termed GLIB (GLucosylation, perIodate o...
ORGANISM(S): Mus musculus 
2011-04-21 | E-GEOD-28682 | biostudies-arrayexpress
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