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MetabolomicsMultiomic profiling of iron-deficient infant monkeys reveals alterations in neurologically important biochemicals in serum and cerebrospinal fluid before the onset of anemia

The effects of iron deficiency (ID) during infancy extend beyond the hematologic compartment and include short- and long-term adverse effects on many tissues including the brain. However, sensitive biomarkers of iron-dependent brain health are lacking in humans. To determine whether serum and cer...

2022-07-12 | MTBLS3388 | MetaboLights
ProteomicsMultiomic Profiling of Iron Deficient Infant Monkeys Reveals Alterations in Neurologically Important Biochemicals in Serum and CSF Prior to the Onset of Anemia
Background: The effects of iron deficiency anemia (IDA) during infancy extend beyond the hematologic compartment and include short- and long-term adverse effects on many tissues including the brain. However, biomarkers of iron-dependent brain health are lacking in humans. Prior analyses in rhesus in...
ORGANISM(S): Macaca mulatta (Rhesus macaque) 
2022-03-18 | PXD028275 | Pride
Infancy Lc-msms Proteomics Acute phase Metabolomics Monkey Tmt Serum Csf Neurological function Iron deficiency anemia Synaptogenesis 
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