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TranscriptomicsMicrosatellite stable (n=38) and instable-high (n=13) human colorectal tumors assayed with Affymetrix HuGeneFL arrays.
mRNA assays were performed on 51 samples of human colorectal tumors using Affymetrix HuGeneFL arrays containing 7129 probe-sets. We compared 38 microsatelite stable (MSS) tumors with 13 microsatellite instable-high (MSI) tumors to form a list of genes differing between the two types. In order to i...
ORGANISM(S): Homo sapiens 
2009-04-10 | E-GEOD-11543 | biostudies-arrayexpress
TranscriptomicsMRE11 Deficiency Increases Sensitivity to Poly(ADP-ribose) Polymerase Inhibition in Microsatellite Unstable Colorectal Cancers.
We have performed bioinformatic approaches to identify the level of enrichment between gene expression profiles characterizing MSI tumors and gene changes induced in vitro by the PARP-1 inhibitor Phenanthridinone and others using the Connectivity Map tool. In a first step, we have anyzed the express...
ORGANISM(S): Homo sapiens 
2011-04-07 | E-GEOD-26682 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling identifies HMGA2 as a novel gene in melanoma progression
The identification of novel tumor-specific markers may improve understanding of melanoma progression and prognostic accuracy. Whole genome expression profiling of 46 primary melanomas, 12 metastases, and 16 normal skin samples using Affymetrix U133 PLUS 2.0 array generated gene lists including both ...
ORGANISM(S): Homo sapiens 
2012-06-07 | E-GEOD-15605 | biostudies-arrayexpress
UnknownClinical Characteristics and Outcomes of Central Nervous System Tumors Harboring NTRK Gene Fusions.
Not available
S-EPMC11788648 | biostudies-literature
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