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TranscriptomicsGenome wide transcriptional profiling of c-Cbl deficient hematopoietic stem and progenitor cells
Expression of genes that are differentially expressed between c-Cbl control and c-Cbl mutant hematopoietic stem and progenitor cells were identified through this approach. Interestingly, several leukemia associated genes, particularly transcription factors, were differentially expressed between c-Cb...
ORGANISM(S): Mus musculus 
2010-08-12 | E-GEOD-23564 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of early dendritic cell DC development in hematopoietic progenitor cell line FDCP-mix that is permissive for DC differentiation in the presence of GMCSF
To identify transcription factors that control dendritic cell development, we performed transcriptional profiling analyses of the murine hematopoietic progenitor cell line FDCP-mix that is permissive for DC differentiation in the presence of GMCSF.We reasoned that GM-CSF modulates a defined set of d...
ORGANISM(S): Mus musculus 
2004-08-18 | E-MEXP-151 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human EBV transformed cell lines established from patients with a novel immunodeficiency syndrome
Lysosome-related organelles have versatile functions including protein and lipid degradation, signal transduction, and protein secretion. The molecular elucidation of rare congenital diseases affecting endosomal/lysosomal biogenesis has given insights into physiological functions of the innate and a...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-6322 | biostudies-arrayexpress
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