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UnknownPolygenic risk scores improve CAD risk prediction in individuals at borderline and intermediate clinical risk
Not available
S-EPMC12912298 | biostudies-literature
UnknownInterleukin-17 receptor A (IL-17RA) as a central regulator of the protective immune response against Giardia.
Not available
S-EPMC5561107 | biostudies-literature
UnknownMechanisms Underlying the Functional Cooperation Between PPARα and GRα to Attenuate Inflammatory Responses.
Not available
S-EPMC6695567 | biostudies-literature
UnknownCompound A influences gene regulation of the Dexamethasone-activated glucocorticoid receptor by alternative cofactor recruitment.
Not available
S-EPMC5556032 | biostudies-literature
UnknownCrosstalk interactions between transcription factors ERRα and PPARα assist PPARα-mediated gene expression.
Not available
S-EPMC11059514 | biostudies-literature
UnknownPharmacological levels of Withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells.
Not available
S-EPMC3912072 | biostudies-literature
ProteomicsThe auophagy receptor SQSTM1/p62 mediates anti-inflammatory actions of the selective NR3C1/glucocorticoid receptor modulator compound A (CpdA) in macrophages
Glucocorticoids are widely used to treat inflammatory disorders; however, prolonged use of glucocorticoids results in side effects including osteoporosis, diabetes and obesity. Compound A (CpdA), identified as a selective NR3C1/glucocorticoid receptor (nuclear receptor subfamily 3, group C, member 1...
ORGANISM(S): Mus musculus (Mouse) 
2019-06-11 | PXD012121 | Pride
Autophagy  autophagy receptors  cpda  glucocorticoids  inflammation  nfe2l2/nrf2  sqstm1/p62 
TranscriptomicsPharmacological levels of Withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells
Withaferin A isolated from Withania somnifera (Ashwagandha) has recently become an attractive phytochemical under investigation in various preclinical studies for treatment of different cancer types. In the present study, a comparative pathway-based transcriptome analysis was applied in epithelial-l...
ORGANISM(S): Homo sapiens 
2014-04-01 | E-GEOD-53049 | biostudies-arrayexpress
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