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ModelsBecker2010_EpoR_AuxiliaryModel
This is the auxiliary model described in the article: Covering a Broad Dynamic Range: Information Processing at the Erythropoietin Receptor Verena Becker, Marcel Schilling, Julie Bachmann, Ute Baumann, Andreas Raue, Thomas Maiwald, Jens Timmer and Urs...
2024-09-02 | BIOMD0000000272 | BioModels
ModelsBecker2010_EpoR_CoreModel
This is the core model described in the article: Covering a Broad Dynamic Range: Information Processing at the Erythropoietin Receptor Verena Becker, Marcel Schilling, Julie Bachmann, Ute Baumann, Andreas Raue, Thomas Maiwald, Jens Timmer and Ursula K...
2024-09-02 | BIOMD0000000271 | BioModels
TranscriptomicsIL13_0-12h_RAIA_et_al
Primary mediastinal B-cell lymphoma (PMBL) and classical Hodgkin lymphoma (cHL) share a frequent constitutive activation of Janus-activated kinase (JAK) / signal transducer and activator of transcription (STAT) signaling pathway. Due to complex non-linear relations within the pathway, key dynamic pr...
ORGANISM(S): Homo sapiens 
2010-12-09 | E-GEOD-23591 | biostudies-arrayexpress
ModelsBachmann2011_JAK2-STAT5_FeedbackControl
This model is from the article: Division of labor by dual feedback regulators controls JAK2/STAT5 signaling over broad ligand range. Bachmann J, Raue A, Schilling M, Böhm ME, Kreutz C, Kaschek D, Busch H, Gretz N, Lehmann WD, Timmer J, Klingmüller U. ...
2024-09-02 | BIOMD0000000347 | BioModels
ModelsPanRTK model for single cell line
Hass2017-PanRTK model for single cell line The model structure comprises heterodimerization and receptor trafficking as described in detail in the article below. For ligand input, set a respective event. The illustrated event sets the EGF concentration to 2.5 nMol in the model file. This model is...
MODEL1708210000 | BioModels
ModelsRaia2011 - IL13 L1236
This is the model of IL13 induced signalling in L1236 cells described in the article: Dynamic Mathematical Modeling of IL13-Induced Signaling in Hodgkin and Primary Mediastinal B-Cell Lymphoma Allows Prediction of Therapeutic Targets. Raia V, Schillin...
2024-09-02 | BIOMD0000000314 | BioModels
ModelsRaia2010 - IL13 Signalling MedB1
This is the model of IL13 induced signalling in MedB-1 cell described in the article: Dynamic Mathematical Modeling of IL13-Induced Signaling in Hodgkin and Primary Mediastinal B-Cell Lymphoma Allows Prediction of Therapeutic Targets. Raia V, Schilling M, Böhm M, Hahn B, Kowarsch A,...
2024-09-02 | BIOMD0000000313 | BioModels
ModelsBachmann2011 - Division of labor by dual feedback regulators controls JAK2/STAT5 signaling over broad ligand range
This is a dynamic pathway model examining the roles of of the two transcriptional negative feedback regulators of the suppressor of cytokine signaling (SOCS) family, CIS and SOCS3, in JAK/STAT5 signaling, within the context of primary erythroid progenitor cells.
2024-09-02 | BIOMD0000000861 | BioModels
ModelsSobotta2017 - IL-6-induced JAK1-STAT3-signaling
Here we present a mathematical model of IL-6-induced JAK1-STAT3 signaling that quantitatively links physiological IL-6 concentrations to the dynamics of IL-6-induced signal transduction and expression of target genes in hepatocytes. The mathematical model consists of coupled ordinary differential eq...
2023-07-05 | MODEL2307050001 | BioModels
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