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TranscriptomicsRNA-seq of murine macrophages (J774A.1 and Raw264.7) grown for 48 hours in conditioned media collected from primary murine Triple Negative Breast Cancer cells
The goal of the experiment was to demonstrate if the overexpression of human-Prune-1 in Triple Negative breast cancer cells induces M2-polarization of macrophages in vitro. For this purpose, murine primary cells from breast tumor developed by Genetically Engineered Mouse Models (GEMMs) of TNBC (i.e....
ORGANISM(S): Mus musculus 
2020-12-03 | E-MTAB-9231 | biostudies-arrayexpress
ProteomicsProteomics investigation of the time course responses of RAW264.7 macrophages to infections with the wild-type and twin-arginine translocation mutant strains of Brucella melitensis
Brucella, a notorious intracellular pathogen, causes chronic infections in many mammals, including humans. The twin-arginine translocation (Tat) pathway transports folded proteins across the cytoplasmic membrane; protein substrates translocated by Brucella include ABC transporters, oxidoreductases, ...
ORGANISM(S): Mus musculus (Mouse) 
2021-07-05 | PXD024658 | Pride
Brucella melitensis  twin-arginine protein translocation  immune response  raw264.7 cell model 
TranscriptomicsExpression data from RAW264.7 murine macrophages infected with Toxoplasma gondii and subsequently stimulated with interferon-gamma
Toxoplasma strains are known to inhibit the expression of several interferon-gamma induced genes, and a type II strain was shown to dysregulate genome-wide responses to interferon-gamma in human fibroblasts (Kim et al., 2007, J Immunol.). In this study we aimed to determine the effect of infection ...
ORGANISM(S): Mus musculus 
2013-02-19 | E-GEOD-34913 | biostudies-arrayexpress
MetabolomicsNorbergenin prevents LPS-induced inflammatory responses in macrophages through inhibiting NFkB, MAPK and STAT3 activation and blocking metabolic reprogramming

Inflammation is thought to be a key cause of many chronic diseases and cancer. However, current therapeutic agents to control inflammation have limited long-term use potential due to various side-effects. This study aimed to examine norbergenin, a constituent of traditional anti-inflammatory reci...

2023-04-06 | MTBLS7127 | MetaboLights
GenomicsmiRNA expression profiles of murine macrophages (cell line: RAW264.7)
miRNA expression profiles of murine macrophages (cell line: RAW264.7)
PRJNA684306 | ENA
GenomicsmRNA expression profiles of murine macrophages (cell line: RAW264.7)
mRNA expression profiles of murine macrophages (cell line: RAW264.7)
PRJNA684304 | ENA
TranscriptomicsLXR activation in RAW264.7 mouse macrophages expressing LXRalpha.
To identify novel LXR target genes, we conducted transcriptional profiling studies using RAW264.7 cells ectopically expressing LXRalpha Total RNA was isolated from RAW264.7 macrophages ectopically expressing LXRalpha as described in Venkateswaran et al. (2000); PNAS 97, 12097-12102. Cells were cult...
ORGANISM(S): Mus musculus 
2009-08-01 | E-GEOD-17088 | biostudies-arrayexpress
TranscriptomicsCharacterization of the chemokine response of RAW264.7 cells to infection by murine norovirus
RAW264.7 macrophages infected with MNV-1 and mock infected gene expression measured by microarray. To be published in Waugh, E. Chen, A. Baird, M. Fleming, S. Brown, C.M. and V K. Ward (2014) Characterization of the chemokine response of RAW264.7 cells to infection by murine norovirus. Virus Genes F...
ORGANISM(S): Mus musculus 
2013-12-22 | E-GEOD-50093 | biostudies-arrayexpress
GenomicsmRNA expression profiles (transcriptome) of murine macrophages (cell line: RAW264.7)
mRNA expression profiles (transcriptome) of murine macrophages (cell line: RAW264.7)
PRJNA595896 | ENA
GenomicsEffect of C2S in RAW264.7 murine macrophages
Effect of C2S in RAW264.7 murine macrophages
PRJNA721606 | ENA
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