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GenomicsChromohalobacter sp. 48-RD10
Chromohalobacter strain 48-RD10 genome sequencing and assembly
PRJNA899692 | ENA
ProteomicsProteomic profiling reveals central role of STAT signaling during retinal degeneration in the rd10 mouse model
The rd10 mouse is a model of retinitis pigmentosa characterized by the dysfunction of a rod-photoreceptor-specific phosphodiesterase. Compared to the rd1 mouse, retinal degeneration in the rd10 mouse begins later in age with a milder phenotype, making it ideal for investigating cell death and neurop...
ORGANISM(S): Mus musculus (Mouse) 
2016-03-21 | PXD002584 | Pride
Label-free mass spectrometry  phospho-stat  retinal müller glial cells 
Transcriptomicsrd10 transcriptome analysis
Retinitis pigmentosa (RP) is a photoreceptor disease that affects approximately 100,000 people in the United States. There are currently very limited treatment options and the prognosis for most patients is progressive vision loss. Unfortunately, the understanding of the molecular underpinnings of R...
ORGANISM(S): Mus musculus 
2014-10-26 | E-GEOD-56473 | biostudies-arrayexpress
ProteomicsRetinal proteomic analysis in rd10 mouse model of retinitis pigmentosa following heterozygous TAK1 deficiency using LC-MS/MS
To decipher the protective mechanisms underlying microglia specific heterozygous TAK1 deficiency in rd10 mouse model of retinitis pigmentosa, we analyzed the retinal proteomic profiles of normal C57BL/6J mice, tamoxifen-treated Cx3cr1CreER/+;Tak1fl/+, vehicle-treated rd10;Cx3cr1CreER/+;Tak1fl/+, and...
ORGANISM(S): Mus musculus (Mouse) 
2025-04-17 | PXD061300 | Pride
Retina Mouse Tak1 Retinitis pigmentosa Lc-ms/ms 
UnknownOptimal timing for activation of sigma 1 receptor in the Pde6brd10/J (rd10) mouse model of retinitis pigmentosa.
Not available
S-EPMC7808329 | biostudies-literature
Transcriptomicsrd10 transcriptome analysis
Retinitis pigmentosa (RP) is a photoreceptor disease that affects approximately 100,000 people in the United States. There are currently very limited treatment options and the prognosis for most patients is progressive vision loss. Unfortunately, the understanding of the molecular underpinnings of R...
ORGANISM(S): Mus musculus 
2014-10-26 | GSE56473 | GEO
UnknownPharmacological analysis of intrinsic neuronal oscillations in rd10 retina.
Not available
S-EPMC4053359 | biostudies-literature
TranscriptomicsA combination treatment based on drug repurposing demonstrates mutation-agnostic efficacy in pre-clinical retinopathy models [scRNA-seq: Rd10]
To determine the gene expression changes in the retina of 2-month-old Rd10 mice reared in darkness throughout their lifespan, we collected retina samples from Rd10 and WT (C57BL/6J mice) mice, generated single-cell suspensions, and performed scRNA-Seq (10X Genomics). One group of Rd10 mice was treat...
ORGANISM(S): Mus musculus 
2024-06-06 | GSE234797 | GEO
GenomicsA combination treatment based on drug repurposing demonstrates mutation-agnostic efficacy in pre-clinical retinopathy models [scRNA-seq: Rd10]
A combination treatment based on drug repurposing demonstrates mutation-agnostic efficacy in pre-clinical retinopathy models [scRNA-seq: Rd10]
PRJNA983249 | ENA
GenomicsHalofantrine protects photoreceptors in multiple models of retinal degeneration [rd10]
Halofantrine protects photoreceptors in multiple models of retinal degeneration [rd10]
PRJNA1450705 | ENA
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