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UnknownHPeak: an HMM-based algorithm for defining read-enriched regions in ChIP-Seq data.
Not available
S-EPMC2912305 | biostudies-literature
UnknownEvaluation of a Web-based tailored intervention (TAVIE en sante) to support people living with HIV in the adoption of health promoting behaviours: an online randomized controlled trial protocol.
Not available
S-EPMC4603806 | biostudies-literature
TranscriptomicsRNAseq of 6 medulloblastoma cell lines
Medulloblastoma is subdivided into different subgroups: WNt, SHH, Group 3 and Group 4. Since these subgroups are associated with different OS and metastasis rates it is crucial to understand them better. Six medulloblastoma cell lines, DAOY, ONS-76, D458, HD-MB03, CHLA-01-MED, CHLA-01R-MED, have bee...
ORGANISM(S): Homo sapiens 
2022-03-02 | E-MTAB-9823 | biostudies-arrayexpress
TranscriptomicsHigh resolution analysis of genomic imprinting in the embryonic and adult mouse brain AND Sex-specific imprinting in the mouse brain
Genomic imprinting results in the preferential expression of the paternal, or maternal allele of certain genes. We have performed a genome-wide characterization of imprinting in the mouse embryonic and adult brain using F1 hybrid mice generated from reciprocal crosses of CASTEiJ and C57BL/6J mice. ...
ORGANISM(S): Mus musculus 
2010-07-08 | E-GEOD-22131 | biostudies-arrayexpress
GenomicsA Genome-Wide Association Study on Cataract and HDL in the Personalized Medicine Research Project Cohort

The primary goals of this project are to develop and validate electronic phenotyping algorithms, to accurately identify cases and controls while maintaining a positive predictive value (PPV) of >95%, and to conduct a genome wide association study that advances understanding of two specif...

phs000170.v1.p1 | EGA
TranscriptomicsEffective requesting method to detect fusion transcripts in chronic myelomonocytic leukemia RNA-seq
Two sets of 10 samples from patients with CMML were used for this study. The first set (CMML11 to CMML20) includes 10 blood samples supplied by Eric Jourdan (Biological Resource Center CHU-Nimes, France). Peripheral blood mononuclear cells were separated by Ficoll-Hypaque density gradient and preser...
ORGANISM(S): Homo sapiens 
2025-07-22 | E-MTAB-13763 | biostudies-arrayexpress
TranscriptomicsMolecular phenotyping of multiple mouse strains under metabolic challenge uncovers Elovl2 as a novel regulator of glucose-induced insulin secretion
Defective insulin secretion by pancreatic β cells underlies the development of type 2 diabetes (T2D). High fat diet-fed mice are commonly used to study diabetes progression, but studies are usually limited to a single strain, such as C57Bl/6J. Here, we use a systems biology approach to integrate la...
ORGANISM(S): Mus musculus 
2017-04-28 | E-GEOD-78183 | biostudies-arrayexpress
TranscriptomicsscRNA-seq analysis of lung neutrophils from mice, 24 hours after intranasal exposure to vehicle, 100 ng LPS and 10 µg LPS
Mice intranasally exposed to a low dose of LPS (i.e., 100 ng) are prone to develop features of allergic asthma upon subsequent exposure to house dust mites (HDM) allergens, while mice exposed to vehicle or 100 µg LPS do not develop such features. In order to understand the mechanisms that promote al...
ORGANISM(S): Mus musculus 
2019-07-25 | E-MTAB-6902 | biostudies-arrayexpress
GenomicsRearrangements of the MAST Kinase and Notch Gene Families in Breast Cancer

Paired-end transcriptome sequencing was performed on a panel of breast cancer cell lines and tissues and a set of benign cell line and tissue controls. Analyses of the paired end sequences were performed and chimeric transcripts derived from gene rearrangement events were identified. Sequencing w...

phs000513.v1.p1 | EGA
TranscriptomicsSingle cell analysis of SHH-patterned hESCs
Single-cell sequencing of floor plate-like cells from synNotch co-cultures expressing Sonic Hedgehog
ORGANISM(S): Homo sapiens 
2025-05-08 | E-MTAB-15075 | biostudies-arrayexpress
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