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ORGANISM(S): Carpus carpio 
Seasonal changes in nitrogen assimilation have been studied in the western English Channel by sampling at approximately weekly intervals for 12 months. Nitrate concentrations showed strong seasonal variations. Available nitrogen in the winter was dominated by nitrate but this was close to limit of d...
ORGANISM(S): synthetic construct 
Proteins can be targeted for degradation by using engineered molecular conjugates to enhance their interaction with eukaryotic ubiquitination machinery. For instance, the fusion of an E3 ubiquitin ligase to a suitable target binding domain creates a biological ‘Proteolysis-Targeting Chimera’ (bioPRO...
ORGANISM(S): Homo sapiens (Human) 
2024-09-23 | PXD041225 | Pride
GWAS study of families with probands with IgA nephropathy from the UK Glomerulonephritis DNA bank
Data Access Committee EGAC00000000013
Samples from the UK Glomerulonephritis DNA bank
Sirtuin 1 (Sirt1) has been reported to be a critical positive regulator of glucose-stimulated insulin secretion in pancreatic beta-cells. The effects on islet cells and blood glucose levels when Sirt1 is deleted specifically in the pancreas are still unclear.This study examined islet glucose respons...
ORGANISM(S): Mus musculus 
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