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GenomicsGene expression profile of CD4+ CD25- T cells in coculture with regulatory B cells expressing granzyme B (GZMB+Bregs) or total B cells
Gene expression profile of CD4+ CD25- T cells in coculture with regulatory B cells expressing granzyme B (GZMB+Bregs) or total B cells
PRJNA934570 | ENA
GenomicsRegulatory B cells expressing granzyme B (GZMB+Bregs)
Regulatory B cells expressing granzyme B (GZMB+Bregs)
PRJNA931282 | ENA
GenomicsGene expression profile at single cell level of in vitro induced regulatory B cells expressing granzyme B (GZMB+Bregs) and non-Bregs from healthy donors and kidney transplant recipients.
Gene expression profile at single cell level of in vitro induced regulatory B cells expressing granzyme B (GZMB+Bregs) and non-Bregs from healthy donors and kidney transplant recipients.
PRJNA934568 | ENA
TranscriptomicsGene expression profile of CD4+ CD25- T cells in coculture with regulatory B cells expressing granzyme B (GZMB+Bregs) or total B cells
Regulatory B cells are considered as a very heterogenous population of different origin and functions. Here, we show that Notably, Bregs induced a strong inhibition of T cell genes associated to proliferation, activation, inflammation and apoptosis compared to total B cells. We identified and valida...
ORGANISM(S): Homo sapiens 
2023-08-23 | GSE224456 | GEO
TranscriptomicsGene expression profile at single cell level of in vitro induced regulatory B cells expressing granzyme B (GZMB+Bregs) and non-Bregs from healthy donors and kidney transplant recipients.
Regulatory B cells are considered as a very heterogenous population of different origins and functions. We used single cell RNA sequencing (scRNA-seq) to analyze the regulatory B cells expressing granzyme B (GZMB+Bregs).
ORGANISM(S): Homo sapiens 
2023-08-23 | GSE224460 | GEO
TranscriptomicsTranscription profiling by array to investigate how Aryl hydrocarbon receptor governs a transcriptional programme that determines regulatory B cell differentiation and function
Regulatory B cells (Breg) play a critical role in the control of autoimmunity and inflammation. Although IL-10 is considered the hallmark for the identification of Bregs, the molecular programme that controls IL-10 production in Bregs is yet to be defined. Here, we demonstrate that aryl hydrocarbon ...
ORGANISM(S): Mus musculus 
2019-10-15 | E-MTAB-7375 | biostudies-arrayexpress
TranscriptomicsRNASeq: Aryl hydrocarbon receptor governs a transcriptional programme that determines regulatory B cell differentiation and function
Regulatory B cells (Breg) play a critical role in the control of autoimmunity and inflammation. Although IL-10 is considered the hallmark for the identification of Bregs, the molecular programme that controls IL-10 production in Bregs is yet to be defined. Here, we demonstrate that aryl hydrocarbon ...
ORGANISM(S): Mus musculus 
2019-10-15 | E-MTAB-7345 | biostudies-arrayexpress
TranscriptomicsA regulatory CD9+ B cell subset controls HDM-induced allergic airway inflammation
Background: A specific subset of regulatory IL-10 producing B cells has been extensively studied in autoimmune and inflammatory pathologies. These cells are able to constrain exacerbated inflammation by inhibiting T cell mediated responses and maturation of antigen presenting cells. In allergic dise...
ORGANISM(S): Mus musculus 
2015-03-01 | E-GEOD-57772 | biostudies-arrayexpress
TranscriptomicsCD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells
Regulatory B cells (Breg) express high levels of CD1d that presents lipid antigens to invariant natural killer T (iNKT) cells. The function of CD1d in Breg biology and iNKT cell activity during inflammation remains unclear. Here we show, using chimeric mice, cell depletion and adoptive cell transfer...
ORGANISM(S): Mus musculus 
2018-01-25 | E-MTAB-6381 | biostudies-arrayexpress
UnknownProperties of regulatory B cells regulating B cell targets.
Not available
S-EPMC8639638 | biostudies-literature
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