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UnknownEngineering Single-Chain Antibody Fragment (scFv) Variants Targeting A Disintegrin and Metalloproteinase-17 (ADAM-17).
Not available
S-EPMC12838881 | biostudies-literature
UnknownTelehealth interventions to reduce management complications in type 1 diabetes: A review.
Not available
S-EPMC4398894 | biostudies-literature
UnknownImmunosuppressive effects of the traditional Chinese herb Qu Mai on human alloreactive T cells.
Not available
S-EPMC3640757 | biostudies-literature
TranscriptomicsSingle-cell RNA-seq of a three-dimensional multilineage human organogenesis model showing endothelial-to-hematopoietic-transition in vitro
Multilineage differentiation of human embryonic stem cells into three-dimensional (3-D) model, termed as progressed elongated embryoid bodies (peEBs), recapitulates crucial features of early human development, including cardio myogenesis and haematopoiesis. Characterisation of peEBs at transcriptome...
ORGANISM(S): Homo sapiens 
2025-01-31 | E-MTAB-13632 | biostudies-arrayexpress
TranscriptomicsExpression Profiling of a Genetic Animal Model of Depression
Expression Profiling of a Genetic Animal Model of Depression Reveals Novel Molecular Pathways Underlying Depressive-like Behaviours In this study we have used genome-wide microarray expression profiling of the hippocampus and prefrontal/frontal cortex of Flinders Depression Sensitive (FSL) and cont...
ORGANISM(S): Rattus norvegicus 
2010-04-01 | E-GEOD-20388 | biostudies-arrayexpress
TranscriptomicsLong read RNA-seq of Plasmodium falciparum 3D7 for annotation of long non-coding RNAs
Important regulation occurs at the level of transcription in Plasmodium falciparum and growing evidence suggests that these apicomplexan parasites have complex regulatory networks. Recent studies implicate long noncoding RNAs (lncRNAs) as transcriptional regulators in P. falciparum and as part of th...
ORGANISM(S): Plasmodium falciparum 
2022-06-10 | E-MTAB-11766 | biostudies-arrayexpress
MetabolomicsMapping immune variation and var gene switching in naive hosts infected with Plasmodium falciparum
Falciparum malaria is clinically heterogeneous and the relative contribution of parasite and host in shaping disease severity remains unclear. We explored the interaction between inflammation and parasite variant surface antigen (VSA) expression, asking whether this relationship underpins the variat...
2020-12-02 | MTBLS1188 | MetaboLights
TranscriptomicsRNA-seq analysis of POLDIP2 mutant in Drosophila melanogaster
Maternal inheritance of mitochondrial DNA (mtDNA) is highly conserved in metazoans. While many species eliminate paternal mtDNA during late sperm development to foster maternal inheritance, the regulatory mechanisms governing this process remain elusive. Through a large-scale genetic screen in Droso...
ORGANISM(S): Drosophila melanogaster 
2024-06-10 | E-MTAB-14104 | biostudies-arrayexpress
TranscriptomicsGraphene Oxide Substrate Promotes Neurotrophic Factor Secretion and Survival of Human Schwann-Like Adipose Mesenchymal Stromal Cells - RNAseq
Mesenchymal stromal cells from adipose tissue (AD-MSCs) exhibit favourable clinical traits for autologous transplantation and can develop a ‘Schwann-like’ phenotype (sAD-MSCs) to improve peripheral nerve regeneration, where severe injuries yield insufficient recovery. However, sAD-MSCs regress witho...
ORGANISM(S): Homo sapiens 
2021-03-08 | E-MTAB-10078 | biostudies-arrayexpress
GenomicsPOLDIP2 is required for mtDNA elimination during spermatogenesis to ensure maternal inheritance in Drosophila melanogaster
Maternal inheritance of mitochondrial DNA (mtDNA) is highly conserved in metazoans. While many species eliminate paternal mtDNA during late sperm development to foster maternal inheritance, the regulatory mechanisms governing this process remain elusive. Through a large-scale genetic screen in Droso...
ORGANISM(S): Drosophila melanogaster 
2024-06-04 | E-MTAB-14100 | biostudies-arrayexpress
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