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TranscriptomicsTranscriptional Landscape of Psoriasis Identifies the Involvement of IL36 and IL36RN
Background: In present study we performed whole transcriptome analysis in plaque psoriasis patients and compared lesional skin with non-lesional skin and with the skin from healthy controls. We sequenced total RNA from 12 lesional (LP), 12 non-lesional (NLP) and from 12 normal (C) skin biopsies. Res...
ORGANISM(S): Homo sapiens 
2015-04-24 | E-GEOD-66511 | biostudies-arrayexpress
TranscriptomicsExposure to 60 minutes of hyperoxia upregulates myocardial humanins in patients with coronary artery disease
Background. In experimental setting the concept of myocardial preconditioning-by hyperoxia has been introduced and different intracellular protective mechanisms and their effects have been described. To study whether similar protective phenotype can be induced by hyperoxia also in humans, gene expre...
ORGANISM(S): Homo sapiens 
2015-02-25 | E-GEOD-66249 | biostudies-arrayexpress
TranscriptomicsRNA-Sequencing Identifies Novel Imprinted Genes in Human Placenta (SNP genotyping)
Fetal health is dependent upon the epigenetic-based regulation of gene expression in placenta. Genomic imprinting is an epigenetic phenomenon common to placenta and refers to the monoallelic expression of a gene in a parental-specific manner. We aimed to detect novel imprinted genes in human placent...
ORGANISM(S): Homo sapiens 
2014-09-01 | E-GEOD-56685 | biostudies-arrayexpress
TranscriptomicsUsing RNA sequencing for identifying gene imprinting and random monoallelic expression in human placenta (RNA-seq)
Given the possible critical importance of placental gene imprinting and random monoallelic expression on fetal and infant health, most of those genes must be identified, in order to understand the risks that the baby might meet during pregnancy and after birth. Therefore, the aim of the current stud...
ORGANISM(S): Homo sapiens 
2014-09-01 | E-GEOD-56524 | biostudies-arrayexpress
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