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MetabolomicsAzithromycin promotes relapse by disrupting immune and metabolic networks after allogeneic stem cell transplantation
Administration of azithromycin after allogeneic hematopoietic stem cell transplantation for hematological malignancies has been associated with relapse in a randomized phase 3 controlled clinical trial. Studying 240 samples from patients randomized in this trial is a unique opportunity to better und...
2022-08-22 | MTBLS406 | MetaboLights
TranscriptomicsTranscription profiling of human ALL patients with first bone marrow relapse
Gene expression profiles were analyzed from 60 children with first bone marrow relapse. Genes and pathways differentiating early vs. late relapse were identified. Signatures predicting early response to therapy were also identified. Experiment Overall Design: 60 patients at relapse were analyzed
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-3911 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human ALL - 35 patients at diagnosis and relapse
35 paired samples from initial diagnosis and first marrow relapse. Genes and pathways differentiating diagnosis and relapse were identified. Potential therapeutic targets were also identified. Experiment Overall Design: 35 patients with samples from initial diagnosis and first marrow relapse.
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-3910 | biostudies-arrayexpress
TranscriptomicsExpression data from ALL diagnosis and relapse pediatric acute lymphoblastic leukemia cases
There is a distinct signature of differentially expressed probes from diagnosis to relapse Gene expression profiles of pediatric patients with B-precursor ALL were compared to at 2 time points, diagnosis and relapse. The overall design was a comparison of gene expression at diagnosis and relapse wit...
ORGANISM(S): Homo sapiens 
2011-09-23 | E-GEOD-28460 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human ALL patients, first bone marrow relapse with or without initial diagnosis
This SuperSeries comprises the following subset Series:; GSE3910: 35 patients at diagnosis and relapse; GSE3911: 60 samples obtained at relapse Experiment Overall Design: Refer to individual Series
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-3912 | biostudies-arrayexpress
GenomicsAnaplasma marginale str. Florida Relapse
Anaplasma marginale str. Florida Relapse genome sequencing
PRJNA64633 | ENA
TranscriptomicsExcessive Cytolytic Responses Predict Tuberculosis Relapse After Apparently Successful Treatment
Background Identification of patients at risk of tuberculosis relapse following treatment would revolutionize clinical trials of new drugs and regimens and facilitate clinical management. The study aim was to determine whether tuberculosis patients who subsequently suffer relapse have different immu...
ORGANISM(S): Homo sapiens 
2015-09-10 | E-GEOD-67589 | biostudies-arrayexpress
ProteomicsDiscovery of biomarker candidates associated with the risk of short- and long-term relapse after infliximab withdrawal in Crohn’s patients: a proteomics-based study
Objective: A subset of Crohn’s disease (CD) patients experiences long-term remission after infliximab withdrawal. Biomarkers are needed to identify those patients. Design: New biomarkers of relapse were searched in the baseline serum of CD patients stopping infliximab when they were under combined t...
ORGANISM(S): Homo Sapiens 
2020-11-02 | PXD019434 | panorama
TranscriptomicsMinor clone provides a reservoir for relapse in multiple myeloma
In this study we addressed subclonal evolutionary process after treatment and subsequent relapse in multiple myeloma (MM) in a cohort of 24 MM patients treated either with conventional chemotherapy or with the proteasome inhibitor, bortezomib. Because MM is a highly heterogeneous disease coupled wit...
ORGANISM(S): Homo sapiens 
2013-02-13 | E-GEOD-37469 | biostudies-arrayexpress
TranscriptomicsComprehensive genomic analysis of relapse neuroblastoma [gene expression]
Relapse neuroblastoma were characterized by sequencing, gene expression, arrayCGH and genome-wide methylation. Here we describe the expression data. Array from tumours at relapse were compared to pretreatment tumours and corresponding normal samples.
ORGANISM(S): Homo sapiens 
2015-06-19 | E-GEOD-65303 | biostudies-arrayexpress
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