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TranscriptomicsGene expression in cells encapsulated within different types of alginate microcapsules
D1 multipotent mesenchymal stromal cells (D1‐MSCs,ATCC® CRL 12424TM) and genetically modified with the lentiviral vector pSIN‐EF2‐Epo‐Pur to express erythropoietin (EPO). D1‐MSCs genetically modified to release EPO were immobilized into 3D alginatepoly‐ L‐lysine‐alginate (APA) microcapsules. Since d...
ORGANISM(S): Mus musculus 
2017-10-30 | E-MTAB-5786 | biostudies-arrayexpress
TranscriptomicsAspergillus fumigatus whole genome transcriptomic study using AWAFUGE microarray after exposition to murine macrophages (RAW 264.7) and human lung epithelial cells (A549).
Aspergillus fumigatus is a filamentous fungus capable to cause an important disease known as invasive aspergillosis. Challenge different cell lines is a crucial strategy to undercover new virulence factors involved in the infection process. In this research, RAW 264.7 macrophages and A549 lung epith...
ORGANISM(S): Aspergillus fumigatus 
2024-01-20 | E-MTAB-13476 | biostudies-arrayexpress
TranscriptomicsAspergillus fumigatus germination process whole genome transcriptomic study using AWAFUGE microarray
Aspergillus fumigatus is a saprophytic fungus that occasionally can produce a wide range of diseases. The ubiquity and great adaptability of this fungus play a crucial role in its pathogenicity. Its adaptation begins in the germination process when it is exposed to the media. In this study pre- and ...
ORGANISM(S): Aspergillus fumigatus 
2024-04-01 | E-MTAB-13921 | biostudies-arrayexpress
TranscriptomicsTranscriptomic study of the pathogenic fungus Aspergillus fumigatus during a murine intranasal infection, using the Whole A. fumigatus Genome Expression 44K v.1 microarray (AWAFUGE).
Aspergillus fumigatus is a saprophytic mold capable of reaching the human deep respiratory system causing different diseases. In this study we tried to detect the virulence mechanisms developed by the fungus, using four days evolution murine intranasal infection model. For that, we develop three ind...
ORGANISM(S): Aspergillus fumigatus Af293 
2018-12-03 | E-MTAB-5314 | biostudies-arrayexpress
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